Israeli forces shot and killed a Palestinian in the occupied West Bank city of Hebron when clashes broke out after Friday prayers, the Palestinian Health Ministry said.
Tensions have soared in recent days after Palestinian assailants killed 11 Israelis in separate attacks across the country. Israeli forces have stepped up security and launched arrest raids in the West Bank, killing two Palestinians during a gunbattle on Thursday.
The Health Ministry said Ahmed al-Atrash, 29, was killed in Hebron on Friday. There was no immediate comment from the Israeli military.
Several hundred Jewish settlers live under heavy military protection in the heart of Hebron, a city of more than 200,000 Palestinians and home to a major holy site sacred to Jews and Muslims.
The Palestinian Red Crescent emergency service said dozens of Palestinians were wounded in weekly demonstrations elsewhere in the West Bank, where protesters often throw rocks and firebombs at Israeli troops, who fire tear gas, rubber-coated bullets and sometimes live rounds.
At the Al-Aqsa mosque in Jerusalem, the third holiest site in Islam, authorities said more than 30,000 people attended Friday prayers on the eve of Ramadan, which begins this weekend. There were no reports of protests or violence.
The hilltop on which the mosque is located is the holiest site for Jews, who refer to it as the Temple Mount, and it has been a frequent flashpoint in the century-old conflict.
Israeli, Palestinian and Jordanian leaders have held a flurry of talks in recent weeks, and Israel has made a series of goodwill gestures, all aimed at calming tensions ahead of Ramadan.
They hope to avoid a repeat of last year, when protests and clashes in Jerusalem during Ramadan ignited an 11-day Gaza war and Jewish-Arab violence in Israel's mixed cities.