Best Joint Supplement For Knees- Which One Is Best For You?

While experiencing joint pain is something that most people will have to deal with in their life, there is a big difference between having your joints ache now and then, to dealing with chronic joint pain that lasts for an extended period of time. While the former may be painful and annoying, the latter can be totally debilitating.

This can be particularly true if you are dealing with joint pain in your knees, as they have to support the weight of your entire body every time you move. This not only makes it hard to alleviate joint pain in the knees, but it also places your cartilage and bone health at great risk if it is left untreated for too long.

Luckily, there are plenty of dietary supplements made to support joint health on the market, you just need to know which one is best for you. That is why we have created this guide to the best joint supplements for knees available today, to ensure that everyone can find the perfect choice to combat joint pain for them.

The 6 Best Joint Health Supplements For Knee Pain

FlexAgain - The Best Joint Supplement For Knee Pain Overall

FlexAgain

FlexAgain is comfortably the best joint pain supplement on the market today. Made using only optimal doses of high quality, scientifically proven, natural ingredients, it is an ideal choice whether you are looking to specifically combat knee pain or simply promote healthy joints in general.

The FlexAgain formula consists of omega 3 fatty acids, curcumin extract (turmeric), glucosamine sulfate, chondroitin sulfate, ginger and blue galangal extracts, bromelain, resveratrol, boswellic acid, MSM (methylsulfonylmethane), vitamin k, and vitamin d.

The main component of FlexAgain is omega 3 fatty acids. Often made from fish oil, they help lubricate the joints, promoting connective tissue growth and providing relief from degenerative diseases like arthritis (1).

A vitamin d deficiency will cause joint pain, so keeping your levels up by taking vitamin d in a supplement will prevent this and stop many other health conditions that could cause joint pain from developing (2).

Vitamin k then serves a very similar purpose, although it has also been shown to be useful for treating osteoarthritis and its symptoms as well (3).

Ginger is known to reduce inflammation, which is one of the top causes of joint pain and a primary reason for it not getting better (4). According to The Arthritis Foundation, combining it with blue galangal extract, a proven bioavailability enhancer, then makes it up to 12 times as effective at relieving joint pain (5).

Boswellic acid, resveratrol, and turmeric supplements are all powerful anti-oxidants and anti inflammatories. They not only ease joint pain but also protect the joints and cartilage from any further damage (6)(7)(8). An active component in turmeric called curcumin blocks free radicals, preventing new inflammation as well.

Chondroitin and glucosamine sulfate supplements are frequently used together as they combine to form one of the best-known joint pain relief remedies. They can be used to combat anything from mild joint discomfort to severe joint pain or arthritis and its symptoms (9).

MSM and bromelain both not only improve joint pain and arthritis symptoms, but they can also restore joint function that may have been lost due to joint inflammation or cartilage degradation (10)(11).

Unlike many joint supplements that use only a few ingredients, the diverse formula that FlexAgain uses lets it provide a multitude of joint health benefits and treat joint pain from every angle. That is why we feel it is the best joint supplement to relieve pain in the knees (or anywhere else) on the market today.

Pros

All of its ingredients are proven to improve joint health
Everything has been optimally dosed to ensure maximum efficacy, without causing any side effects
Can relieve joint pain and restore joint health and functions at the same time
Can treat arthritis pain and symptoms

Cons

A little pricey and only available directly from the official FlexAgain website

Physio Flex Pro - The Best Joint Supplement For Osteoarthritis Pain

Physio Flex Pro is one of the top joint supplements on the market for those dealing with knee osteoarthritis and the chronic pain that it can cause. Despite being made with only natural ingredients, there are claims it can improve joint pain caused by arthritis as well as some of the milder prescription arthritis medications.

Its formula contains many of the same ingredients as FlexAgain, although in different doses, and includes selenium, glucosamine hydrochloride, bromelain, ginger extract, turmeric extract, chondroitin sulfate, MSM, and black pepper fruit extract.

The bromelain, chondroitin sulfate, glucosamine hydrochloride, and MSM will all help to reduce joint pain and restore joint health and functions in the same ways that we saw before.

Selenium is what makes Physio Flex Pro particularly useful for treating osteoarthritis. A compound made naturally by the human body, it can reduce inflammation, boost cartilage growth, synovial fluid production, and joint lubrication and flexibility, while easing joint stiffness, to treat all known arthritis symptoms (12).

Ginger and turmeric are again extremely useful for reducing inflammation. Black pepper fruit extract then has anti-inflammatory properties of its own, but its main selling point is that it can aid the absorption and efficacy of other ingredients in joint supplements, which it can do especially well with turmeric (13).

Admittedly, Physio Flex Pro is one of the pricier supplements for joint health on the market and the range of health benefits that it offers is not nearly as extensive as FlexAgain . However, if you are shopping for joint supplements specifically to treat osteoarthritis and aren't worried about money, it is a very good way to go.

Pros

All its ingredients are proven and suitably dosed for treating joint pain caused by osteoarthritis
Can reduce joint pain and stiffness and improve joint health

Cons

Does not provide such as wide range of joint health benefits as FlexAgain
One of the more expensive joint supplements on the market

U.S. Doctors' Clinical Arthro-7 Healthy Joint Support - The Best Joint Supplement For Rheumatoid Arthritis Pain

Like Physio Flex Pro, U.S. Doctors' Clinical Arthro-7 Healthy Joint Support is designed primarily for people dealing with arthritis, only this time it focuses specifically on rheumatoid arthritis.

A completely GMO and gluten free supplement, its formula consists of vitamin c, collagen, CMO (cetyl myristoleate), lipase 30, MSM, turmeric, and bromelain.

The turmeric will work to reduce inflammation, like it has previously, although the lack of a dedicated bioavailability enhancer will make it a little less effective. The bromelain and MSM will then again look to provide pain relief by repairing the damage to the joint space that is causing the problem.

The vitamin c and collagen are both anti inflammatories that reduce joint swelling and pain, and which work especially well when paired together.

Collagen is also a primary building block of protein, so can aid cartilage and connective tissue growth and joint repair, while reducing muscle soreness and preventing joint pain or issues from getting any worse. The vitamin c then enhances your overall health, to allow this process to occur as smoothly as possible (14)(15).

CMO is a fatty acid often found in fish oil. While not quite as effective as omega 3 fatty acids, studies on complementary and integrative health still show it is a great way to improve joint pain and lubrication (16).

Finally, lipase 30 is an enzyme that improves the breakdown of triglycerides into fatty acids and glycerol. This will help to improve joint mobility and lubrication and reduce arthritis pain even more, while also helping to prevent fat storage and weight gain (17).

There is, however, one quite big issue with U.S. Doctors' Clinical Arthro-7 Healthy Joint Support, and that is the fact that all of its ingredients, with the exception of vitamin c, are lumped together in a single massive proprietary blend.

This makes it impossible for us to know precisely how much of each ingredient is present, limiting our ability to predict the exact results the supplement will produce. However, while this will understandably be a deal breaker for a number of people, the positive reviews from past users it has shows that it does work.

So, if your main concern is treating rheumatoid arthritis, it is still one of the better joint supplements around.

Pros

Reasonably priced and easy to get hold of
Every ingredient in its formula is proven to benefit your joint health
Specifically designed with the main building block of protein to ease joint pain in people suffering with rheumatoid arthritis
Has received positive reviews from people suffering from rheumatoid arthritis

Cons

All of its ingredients except vitamin c being lumped into a single proprietary blend make it impossible to accurately predict what dosages are present or the effects that they will produce

Vimerson Health Vegan Glucosamine Chondroitin Phytodroitin MSM & Burdock Root - The Best Joint Supplements For Vegans

Research suggests fish oil supplements are among the most popular and effective ways for people to treat joint aches and pains. Unfortunately, people who live a vegan or vegetarian lifestyle are unable to use them.

As luck would have it though, there are a small number of plant based joint supplements on the market, of which Vimerson Health Vegan Glucosamine Chondroitin Phytodroitin MSM & Burdock Root is the top choice.

Its formula is 100 percent vegan and consists of vegan glucosamine sulfate sodium, vegan MSM, burdock root 4:1 extract, and a vegan version of chondroitin supplements called phytodroitin.

As we have already seen, the combination of MSM, glucosamine, and chondroitin supplements is extremely popular and effective for combatting joint pain and restoring joint health. The only difference here is where they come from.

The Vimerson supplement uses glucosamine naturally occurring in a type of fungus called aspergillus niger, as well as MSM obtained from a wide variety of plant sources. The really unique version of the three vegan alternatives though is phytodroitin, which is an artificial form of chondroitin produced in a lab.

The formula is then rounded off with burdock root extract, which is a great alternative to fish oil for vegans, as it is full of omega 3 fatty acids. This will not only improve joint lubrication and mobility, but it can also be a part of a well-balanced diet, something that is a little harder to achieve when you only eat plants (18).

There are a couple of issues with this vegan glucosamine and chondroitin supplement we do need to mention though.

Not only have the vegan glucosamine and chondroitin sources been researched less extensively, meaning it is harder to predict both their positive and negative effects but, as plant based ingredients for treating joint pain are less common, they have been used in very high doses, which could cause some side effects.

That said, as reviews from past users claim it does help ease joint pain and inflammation and improve bone and joint health to some degree, with little mention of side effects, Vimerson Health Vegan Glucosamine Chondroitin Phytodroitin MSM & Burdock Root is still a great option for vegans who find their joints ache.

Pros

Burdock root extract is an ideal alternative to fish oil supplements for vegans
Has a very fair price tag
All the ingredients are proven to benefit joint pain, inflammation levels, and bone health

Cons

The vegan chondroitin and glucosamine sulfate are present in very high dosages that could cause side effects
Vegan glucosamine and chondroitin sources are less researched, so it is harder to accurately predict either the positive or negative effects that they will produce

Nuzena Joint Support + - The Best Joint Supplements For People On A Budget

Supplements for joint pain may be effective, but they are also often quite expensive, which can mean that they are unobtainable for some people. Luckily, there are a number of options specifically designed to cater to people on a tighter budget, and Nuzena Joint Support + is a perfect example of such a product.

The Nuzena Joint Support + formula features boswellia extract, bromelain, MSM, turmeric, glucosamine sulfate, chondroitin sulfate, quercetin, and methionine, all of which are approved by the food and drug administation.

Yet again, bromelain, chondroitin, MSM, and glucosamine supplements are included for their proven ability to ease pain and repair any damage to the joint space, while boswellia extract and turmeric both reduce and prevent inflammation.

The flavonoid quercetin is found in various fruits, vegetables, plants, and leafy greens and has been proven to help reduce joint inflammation and treat the symptoms of certain autoimmune diseases, like arthritis (19).

Methionine is an essential amino acid and precursor to numerous antioxidants that can aid cell metabolism, reduce and prevent inflammation, and treat issues caused by illnesses like arthritis or fibromyalgia. It is also shown to be especially effective when paired with a glucosamine supplement like it is here (20).

We do, unfortunately, have to mention that the ingredient dosages in Nuzena Joint Support + are lower than ideal or what you will find in some other joint supplements. However, this is to be expected when you are looking at lower priced supplements such as this.

Supplements containing quercetin also should not be taken by people who are on blood thinners, as they can cause negative interactions.

Despite these drawbacks though, if you are looking for a supplement to reduce inflammation and promote healthy joints while shopping on a budget, and you are not taking blood thinners, there are far worse choices you could make than giving Nuzena Joint Support + a try.

Pros

Each of its ingredients has been proven to reduce inflammation and joint pain
One of the best joint supplements for people seeking a low cost, high value option
Widely available and very easy to obtain

Cons

Aside from glucosamine sulfate, all of its ingredient dosages are far lower than ideal or what you will find in more expensive joint health supplements
Cannot be used by people taking blood thinners

Animal Flex - The Most Popular Joint Health Supplement

Animal Flex is easily one of the most popular joint supplements on the market today, so it is ideal for those who are still unsure about taking one. Produced by well-known fitness brand Universal Nutrition, it is suitable for and used by everyone from pro bodybuilders to those just seeking a little relief from joint pain.

The Animal Flex formula is split into three proprietary blends, which are labelled the Joint Construction Complex, Joint Lubrication Complex, and Joint Support Complex, which aim to repair damaged connective tissues and protect, maintain, and lubricate the joints, while boosting joint health, mobility, and function.

The Joint Construction Complex contains MSM, glucosamine hydrochloride, and chondroitin sulfate a and c. The Joint Lubrication Complex consists of flax seed oil and cetyl myristoleate. Then the Joint Support Complex has ginger root extract, turmeric root extract, boswellia serrata extract, quercetin, and bromelain.

It is then also fortified with a range of vitamins and minerals that includes vitamin c, vitamin e, zinc, selenium, and manganese.

MSM, glucosamine hydrochloride, and chondroitin sulfate can relieve joint pain, reduce inflammation, and treat arthritis and its symptoms, so the Construction Complex is tailored to benefit the whole joint space.

The ginger root extract, turmeric root extract, boswellia serrata extract, quercetin, and bromelain in the Support Complex are all known anti inflammatories that can both reduce and prevent joint swelling, while helping the joints to recover from damage far more quickly.

Then you have have the fatty acid content in the Lubrication Complex supplied by flax seed oil and CMO (cetyl myristoleate). These are great alternatives to fish oil for enhancing joint flexibility, lubrication, and mobility (21).

Last but not least, the vitamins and minerals will boost your immune health and functions, to ensure that your body is in the best state possible to repair and maintain your joints.

There is however a big issue with Animal Flex, which is that with all its ingredients besides the vitamins and minerals lumped together in 3 proprietary blends, there is no way to know what many of the true ingredient doses are (though we can see some are too low) or what effects they will produce, positive or negative.

It is also quite pricey as well, which may be off putting for some people, and can't be used by people on blood thinners, due to the presence of quercetin.

These issues aside though, Animal Flex can be beneficial for your joints. So, if you want to stick to a popular product from a widely used brand and the issues above don't worry you, this may be the joint supplement for you.

Pros

All the ingredients have been proven to benefit joint health in some way
Formulated to relieve joint pain and boost your overall health at the same time
Produced by a very popular and well known brand

Cons

Proprietary blends hide all the ingredient dosages, while some are visibly too low
More proof is required to determine just how effective some of the ingredients will be in a joint supplement
Quite expensive and unsuitable for people taking blood thinning medications
Contains soy and a number of ingredients not suitable for vegetarians

Final Thoughts On The Best joint Supplements For Joint Pain In The Knees

Joint pain in the knees is very common, especially for people who regularly eat foods high in saturated fat or sugar, but it doesn't need to be debilitating, as there are plenty of options for pain relief, like physical therapy. As far as joint health supplements go though, FlexAgain is by far the best option available.

A joint supplement made from only optimal doses of a wide range of proven ingredients, it can restore joint mobility and function, alleviate joint pain and stiffness, reduce joint inflammation and swelling, and even repair damaged connective tissues, to help improve and support joint health from every angle.

If, for any reason, you feel that it is not the right joint supplement for you, then one of the other options on our list of the best joint health supplements for knees surely will be. For everyone else though, we would highly recommend that you give FlexAgain a try and see how useful it is for aiding joint health for yourself.

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