Advertisement
Saturday, Nov 27, 2021
Outlook.com
Outlook.com

IIT Researchers Discover New Molecule To Treat Prostate Cancer

The data says that about 5.56 lakh Indians die of prostate cancer every year.

IIT Researchers Discover New Molecule To Treat Prostate Cancer
Representational picture
IIT Researchers Discover New Molecule To Treat Prostate Cancer
outlookindia.com
2020-09-29T15:18:18+05:30

Researchers at the Indian Institute of Technology (IIT), Gandhinagar, claim to have discovered a new molecule which can be used as a targeted therapy for prostate cancer.

The research in collaboration with scientists at Louisiana State University Health Center, USA and the University of Manchester, has also been published in international journal "Cell Press, iScience".

According to Sivapriya Kirubakaran, Professor at IIT Gandhinagar, who led the research, about 5.56 lakh Indians die of cancer every year, and the increasing resistance to anti-cancer drugs is also of grave concern.

"Prostate cancer, the second most commonly occurring cancer in men worldwide needs a hormone called 'androgen' to grow. The standard treatment method is hormonal therapy or androgen-deprivation therapy (ADT) which provides respite from disease progression. However, it could fail when cancer spreads to other parts of the body leading to a terminal phase of the disease," Kirubakaran told a news agency. 

"We have discovered a new molecule called J54 which has shown great potency not only in cells but also in animals (mice model) to completely reduce tumour (prostate cancer) in 50 days (in male mice). The median time for prostate cancer to shrink in human male patients is about 18 months, some quicker, some slower, depending on the size of tumour detected," she added.

Sivapriya further explained that this molecule is the first selective inhibitor of the protein that causes cancer initiation and growth, mainly in the prostate.

"Since J54 combination therapy is targeted to a specific protein, it is expected to be more effective and personalised for the treatment of a particular patient. It has not shown any side effects or toxicity effects in normal cells and animals. The new molecule completely reduces prostate cancer in mice model.

"Also, the amount of drug used is considerably reduced when compared to known therapy. The efficacy and potency shown by J54 molecule create hope for a faster therapy of prostate cancer. The scientists are confident that the findings pave the way for a new targeted therapy for prostate cancer with fewer side effects, if proved successful in clinical and human trials," she added.

Advertisement

Outlook Newsletters

Advertisement
Advertisement
Advertisement

Read More from Outlook

Roses Among Thorns: The Many Solidarities Of Diverse Protests

Roses Among Thorns: The Many Solidarities Of Diverse Protests

Every act of dissent is an art. Of pain and pathos. Of hope and new dawn. It’s their story. It’s everyone’s story.

Jai Kisan: Success Of Farmers' Protest Proves The Strength Of Their Convictions

Jai Kisan: Success Of Farmers' Protest Proves The Strength Of Their Convictions

Farmers’ movement reaffirms that peasants are makers of their own rebellion.

Pragmatic Shreyas Iyer Wants To 'Stay In The Moment,' Not Thinking Of Kohli’s Return

Pragmatic Shreyas Iyer Wants To 'Stay In The Moment,' Not Thinking Of Kohli’s Return

Shreyas Iyer scored a century on debut in the first IND vs NZ Test in Kanpur. It remains to be seen whether Iyer will play when Virat Kohli returns for the Mumbai Test.

Machimar Nagar: The Fishermen’s Colony;  An Entry Gate For 26/11 Terrorists

Machimar Nagar: The Fishermen’s Colony; An Entry Gate For 26/11 Terrorists

13 years ago on this day, eight terrorists from Pakistan arrived by sea on the shores of this fishermen colony-Machchimar Nagar, to launch an attack in India’s financial capital.

Advertisement