GLP-1 agonists are very much popular these days for weight loss and there are several types available that are sometime prescribed off-label to support weight management goals.
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Weight loss can be a daunting and most challenging task for some people. Even if you are following a proper well-balanced diet routine and exercising program, but the results are not going in your favour, it’s time for you to try out some other methods for weight loss. There are different medications available in the market that supports weight loss and make the journey easier for you.
One popular medication that is recently approved by the Food and Drug Administration is semaglutide. It is available under different brand names, but the most renowned is the Wegovy. This medication is categorized as a GLP-1 agonist that is formulated to help reduce the appetite and calorie consumption, thus eventually supports better weight loss results.
In this article, we will discuss all the necessary details about GLP-1 agonist and the most known medications that can help you get through your weight loss struggles.
GLP-1 Medications for weight loss
GLP-1 medications for weight loss come under different brand names with short-acting and long-acting formulas. Your doctor will prescribe you with the right type of GLP-1 medication according to your medical history, insurance coverage, pricey, personal preference, and blood sugar control efficacy.
Following are the most known GLP-1 medications for weight loss:
1. Ozempic - glp 1 weight loss medication
Ozempic is a semaglutide injection that is approved as the treatment for improving blood sugar management in adults with type 2 diabetes. Though, people usually confuse between Wegovy and Ozempic, but they are not similar.
Ozempic is available generally in the low dose form, which makes it not directly associated with weight loss. Generally, the cost of Ozempic is around 900 USD for a 28 day supply, however, you the price will actually depend on the prescribed dosage, and your insurance and healthcare coverage.
Ozempic – How it Works
Ozempic comes in an injectable form that is needed to be administered once a week. As per the recommendation, you have to start with a small dose of 0.25 mg once a week and gradually you can increase to 0.5 mg after the course of 4 weeks. You should follow your doctor’s advice, as for some patients the weekly dose is allowed to be increased to 1 mg per week.
Clinical studies have supported that Ozempic is a beneficial medication for diabetes management and weight loss.
Ozempic doses of 0.5 mg weekly and 1 mg weekly have found to be more effective than other dulaglutide drugs, which is also a GLP-1 agonist. Not only Ozempic help people in managing their blood sugar levels, but also promotes weight reduction without any discomfort.
Ozempic – Pros & Cons
Following are some of the pros and cons associated with Ozempic drug:
- It is beneficial for supporting blood sugar management.
- It works to increase weight loss.
- It is more effective than other GLP-1 agonist medications.
- It is only administered one time a week.
- You need to administer injections by yourself.
- It is not specifically created for weight loss.
- It is not approved as the weight loss treatment medication.
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2. Saxenda - glp 1 agonist for Weight Loss
Saxenda is one of the popular GLP-1 medication available as the prescribed treatment for weight management. It is a Liraglutide drug that comes in an injectable form and works best when used in combination with healthy diet and active lifestyle. Saxenda is approved for people with obesity and weight struggles with at least one health condition related to weight. The Food and Drug Authority FDA approved Saxenda in 2020 as the weight management medication to be used for children ages 12 and older with obesity.
Usually, the cost of Saxenda medication per month is around $ 1400 to $ 1500. However, it again depends on your insurance and healthcare coverage plan.
Saxenda – How it Works?
It is recommended dose of Saxenda usually prescribed by physicians is 3 mg per day. You should always initiate the use of Saxenda with the starting dose of 0.6 mg per day and elevate the dose in weekly pattern until the recommended dose of 3 mg is reached. Clinical studies have supported that Saxenda medication could be effective for losing weight.
Saxenda users have successfully lost almost 5% to 10% of their body weight over the period of 6 months. Saxenda users have shared that taking 3 mg of Liraglutide per day helps them in shedding 9 pounds of weight after 7 months. However, you should always remember to maintain an active and healthy lifestyle while using Saxenda injections for weight loss.
In addition, despite of the fact that Saxenda is not an approved treatment for managing type 2 diabetes, it has shown great results by supporting blood sugar management.
Saxenda – Pros & Cons
Following are few Pros and Cons associated with the usage of Saxenda medication:
- It is an approved treatment for weight loss.
- It can be used for 12 years of age and older.
- It helps additionally in managing healthy blood sugar levels.
- It must be administered daily.
- It is a self-administered injection treatment for weight loss that could be painful for some.
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3. Wegovy - glp 1 drugs for Weight Loss
Wegovy is a GLP-1 agonist that is approved for weight loss by the FDA in 2021. It is a semaglutide medication that helps people in losing weight. The cost of 28 day supply of Wegovy injection comes for around $ 1400 to $ 1500 per package. However, your insurance coverage plan can help in cutting down some price.
Wegovy – How it Works?
Wegovy is also an injectable treatment that is needed to be administered once per week. For the initial 16 weeks, it is recommended to take small doses of Wegovy, around 0.25 mg and 1.7 mg. After your body gets tolerant with the Wegovy drug, you can then continue with the maintenance dose of 2.4 mg per week for as long as it supports your weight loss goals.
Studies have suggested that taking a maintenance dose of 2.4 mg of Wegovy medication once a week helps in reducing weight and was comparatively more effective than other similar drugs. Wegovy users have experienced an average of 7.9% decrease in body weight with an active and healthy lifestyle.
Besides losing weight on scale, Wegovy users notice a significant reduction in their waist circumference, haemoglobin A1C (HbA1c) levels, systolic blood pressure, total cholesterol levels and triglycerides. Clinical studies have suggested that the results for weight loss by Wegovy are almost double as compared to other GLP-1 agonist Liraglutide medications. Moreover, Wegovy works better for controlling appetite and food cravings, thus leading to controlled calorie consumption for faster weight loss results.
Wegovy – Pros & Cons
Following are the pros and cons associated with the Wegovy medication:
- It is an approved GLP-1 agonist medication for weight loss by FDA.
- It comes with many health benefits, such as improved cardiovascular health, and blood sugar management.
- It is only administered once a week.
- It is far more effective than many other GLP-1 agonist drugs for weight loss, such as Liraglutide.
- They are self-administered injections that might be painful for some.
What is GLP-1?
GLP-1, also known as glucagon-like peptide-1, refers to a diverse group of hormones that are naturally found in the human body.
GLP-1 hormones play a vital role in regulating different physiologic processes of the body, including metabolism and digestion. When a person starts eating, the body naturally releases hormones called GLP-1. Moreover, the activity of the brain that is related to hunger pangs and eating urge is also controlled by hormones GLP-1. The high levels of GLP-1 hormone send the signals to brain that the body is no more feeling hungry and doesn’t need to consume any food.
Therefore, there are medications used to elevate the GLP-1 levels for stimulating its effects that may help in the prevention of excessive food consumption. Most of the people combating with obesity struggle a lot in maintaining a good control over the calories they consume.
This is because, their brains may not have enough GLP-1 hormones, and they may end up in overeating and over consumption of food. The use of GLP-1 drugs therefore helps the people by imitating the actual hormone and preventing hunger pangs and excessive eating.
These drugs may help obese individuals in the long-term management of weight related issues.
What is GLP-1 medication?
GLP-1 medications are currently getting popularity for their ability of losing weight. GLP-1 medication work for weight loss by mimicking a naturally produced hormone called Glucagon-like peptide 1. This plays an important role in regulating your hunger and food consumption.
The release of GLP-1 hormone will actually delay emptying of the stomach, so that food stays for longer time that makes you feel fuller for longer. This process will eventually aids in suppressing another hormone called glucagon, thus prevent you from feeling hungry.
GLP-1 agonists work by binding to GLP-1 receptors to produce the same effects. GLP-1 agonist medications are generally used as the treatment of type 2 diabetes, as the drugs increase the insulin release, a hormone produced by pancreas. This hormone aids in removing excess sugar from the blood, thus regulating your blood sugar levels. Clinical studies have suggested that GLP-1 agonists plays its part in decreasing appetite to promote weight loss.
With such researches, people start using GLP-1 agonists as weight loss medications. However, there are some medications in the market that were specifically created and approved as a proper weight loss drug. Healthcare providers mostly prescribe these medications as a part of your weight loss journey along with low-calorie diet routine and regular exercising regime.
GLP-1 receptor agonists are a drug type that is used by the people having type 2 diabetes to control and regulate their blood sugar levels. GLP-1 hormone is produced in the small intestine. It stimulates the secretion of insulin and inhibits glucagon secretion to lower blood sugar levels. The use of GLP-1 agonist will slow down the emptying of stomach, which means less glucose from food is released into the bloodstream. GLP-1 actually increases the feeling of fullness after eating, which plays its part in offering good weight loss results.
GLP-1 agonist drugs can be taken along, or along with metformin or other diabetes related drugs. This all depends on your own medical condition and blood sugar levels. Shorter-acting GLP-1 particularly affects to lower glucose levels, while the longer-acting GLP-1 offer more balanced effects on lowering post-meal and fasting glucose levels. GLP-1 agonist is not yet approved by the FDA for people having type diabetes. However, some doctors may prescribe it off-label to such patients.
Semaglutide belongs to a class of drugs known as glucagon-like peptide-1 receptor agonists, or most commonly known as GLP-1. Semaglutide is created in a way that it imitates the original GLP-1 hormone, released in the gut in response to food consumption.
One role of GLP-1 is to stimulate the body for more insulin production, which in turn reduces blood sugar levels. That is the reason why doctors have used semaglutide for more than a decade as the treatment of type 2 diabetes.
When GLP-1 hormone is in higher amounts, it also interacts with the brain parts that are responsible for suppressing appetite and sending your body a signal to feel full. When used along with balanced low-calorie diet and workout routine, Semaglutide can cause a significant amount of weight loss. In addition, it also reduces the risk of cancer, diabetes, and cardiovascular issues in the obese and overweight individuals.
GLP-1 Weight loss
Though, Semaglutide GLP-1 injections are popular in the market, but it is only approved for weight loss under the brand named Wegovy. This medication is used for weight loss with the typical dose of 2.4 mg that need to be administered weekly as subcutaneous injections. These injections are used under the skin and can be administered by the user himself.
Due to its impressive weight loss results , the popularity of semaglutide continues to grow and doctors manage to meet the demands with proper ways. Many healthcare professional prescribe different brands of semaglutide off-label, such as Ozempic, to help people manage and lose weight. Though, GLP-1 weight loss medications were approved by the FDA to serve the purpose of diabetes management, but it gained popularity due to weight loss reasons.
Now that we know that GLP-1 lead to weight loss, let’s explore how it actually helps in shed excess weight. GLP-1 suppresses appetite and weight through a complex series of brain-gut reactions. GLP-1 hormone works by stimulating GLP-1 receptors, which leads to the following important effects; such as:
- Increased production of insulin in the body.
- Reducing the release of Glucagon
- Reducing the appetite
- Delaying the gastric emptying to give satiety
GLP-1 helps greatly in losing weight, as it makes the process of stomach emptying slower while regulating the brain’s hunger indications. This makes you completely satisfied even with eating fewer calories and helps in losing weight. Even if you are on GLP-1 medication, your doctor will recommend to follow a healthy diet and consistent active lifestyle.
GLP-1 drugs for weight loss over the counter
Though, GLP-1 drugs for weight loss are quite popular in among the users. However, due to the recent concerns raised about the drugs many people are looking for some safe over the counter weight loss alternative medication.
In addition, many people are not comfortable in using injections and prefer to use safe supplements in oral form. Also, most of these GLP-1 drugs for weight loss come only with doctor’s prescription.
So, if you are looking for an effective weight loss supplement that is available easily over the counter, we will recommend PhenQ.
PhenQ – Over the Counter glp-1 Medication for Weight Loss
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PhenQ is composed of all the proprietary mix ingredients that are all-natural and organic. This revolutionary weight loss supplement is free from any animal products, and therefore suitable for vegans. The highly-effective PhenQ supplement is composed of various botanical herbs and natural extracts that are scientifically proven to promote weight loss and fat burn.
Following are the ingredients included in PhenQ formulation:
- Alpha-Lacys Reset
- Capsimax Powder
- L-Carnitine Fumarate
- Chromium Picolinate
- Nopal Cactus
All these ingredients works synergistically to help people lose stubborn body fat and shed excess pounds naturally.
PhenQ – Benefits
PhenQ fat burning supplement is ideal for improving physical fitness and has the potential for offering various health advantages. Because of its unique approach and natural formula, PhenQ stimulates the body to burn fat effectively and getting rid of fat pockets even from the most stubborn body areas. PhenQ has benefitted a million of users with its formula and people have noticed great improvements in their overall shape and well-being. Following are some of the benefits offered by PhenQ dietary supplement:
- It helps burning body fat effectively by accelerating metabolism.
- It helps in preventing further fat storage in the body, thus prevents from weight gain.
- It works on suppressing appetite and reduces food cravings, thus keeps you on track with a healthy low-calorie diet.
- It offers a burst of energy and improves your mood.
PhenQ – Recommended Dosage
The manufacturer has recommended to use two pills of PhenQ dietary supplement daily. You have to take the first pill in the morning with breakfast, and the second pill in the afternoon with lunch meal. It is recommended to always consult with your doctor before starting any supplement. Also, people who are allergic to any of the PhenQ ingredients should talk with their health consultants prior using this supplement. In addition, if you are pregnant, nursing mom, or are suffering from any chronic illness, you should be cautious while using PhenQ. This dietary supplement is not suitable for children below 18 years of age.
Where to buy GLP-1 Weight loss adlternatives?
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Concluding Thoughts - GLP-1Medication and OTC Alternative for Weight Loss
Though, GLP-1agonist medications are a known and popular treatments for weight loss, but due to their injectable form, these are not a preferable choice to many users. Instead of attaining prescription for using GLP-1 agonist (semaglutide or luraglutide) for achieving good weight loss results, you can get an effective weight loss solution easily over the counter.
PhenQ is a powerful weight loss formula that helps people shed excess pounds and keep that off as well. PhenQ dietary supplement is helpful in burning fat, while offering many other health benefits for overall improvement in well-being.
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