Friday, Jun 09, 2023

Best Berberine Supplement Brands Of 2023: Know About The Berberine Benefits & Reviews

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Best Berberine Supplement Brands Of 2023: Know About The Berberine Benefits & Reviews

We have listed some of the best brands that sell effective berberine supplements on the online market right now. Berberine powder is very effective, but it’s extremely bitter. So, if you think you cannot handle that, a pill may be the best option for you.

Berberine Supplement Brands
Berberine Supplement Brands

Humans have been looking for medical miracles forever. But very often, it’s found that Mother Nature has had that “miracle” up her sleeve all along. It’s rather like a treasure hunt.  

It’s all there. You just need to find it. 

One such treasure is the wonder compound, known as berberine. It is not that berberine is a newly found wonder drug. It has been used in ancient Indian and Chinese medicines for ages. However, its uses and benefits are only now being discovered by modern scientists and researchers in the West. 

The benefits of berberine seem endless.  

It may help those with diabetes, hypertension, fatty liver disease, PCOS, prostate cancer, and even canker sores.  

And oh, just in case we forget — it can even help you lose weight!  

If you’re on a ketogenic diet, adding berberine to your diet could give you an added advantage. Although much of the research on this plant-based alkaloid is still in its nascent stage, what we can say without a doubt is that berberine indeed has quite a lot of therapeutic potential. So, quite unsurprisingly, the US market is already teeming with berberine supplements.  

Since not all of them are equally effective, and some may be outright fake, we have listed some of the best brands of this supplement for you. We will also guide you on how to buy good berberine supplements from the market and all the dos and don’ts regarding the compound — which you must strictly follow. But first, we will tell you which brands made our final list and explain to you how we chose these brands of berberine supplements. 

5 Best Berberine Supplement Online In 2023 

#1. Berberine HCL: Overall Best Berberine Supplement, Editor’s Pick 

#2. Berberine Glucose Support: Most Popular Berberine For Weight Loss 

#3. Berberine Root Extract: Highly Trusted For People With Lower Sugar Levels  

#4. Berberine-500: Recommended Berberine Supplements For Better Heart Health 

#5. Berberine Pure+ : Best Supplement For Lowering Cholesterol Levels 


#1. Berberine HCL: Overall Best Berberine Supplement, Editor’s Pick 

Berberine HCL
Berberine HCL

Bulk Supplements supplies over 500 nutritional supplement-based health products to consumers and manufacturers alike. The company is located in Henderson, Nevada. 

Its products are manufactured in the company’s NSF-certified and FDA-registered cGMP facility. Each supplement is tested in its in-house laboratory, while any and all additional testing is done in a vetted US-based independent lab. 

This product is available in powdered form and will last you at least a month if taken as per the prescribed dosage. The product does not contain sugar, soy, dairy, yeast, or gluten additives.  

Since it is in a powdered form, you can enjoy it with your favorite protein shake, smoothie, or non-caffeinated drinks. It is one of the most effective and affordable options in the berberine market.  

All orders placed on Bulk Supplements’ website are usually processed within 48 hours. Orders received before noon are usually shipped out the same day. The shipping charge starts at a flat rate of $7.95. However, for orders more than $49, shipping is free within the US territories, barring Alaska, Hawaii, and Puerto Rico. Products shipped to the three above-mentioned destinations may incur additional shipping charges. 

Orders worth more than $250.00 are shipped via Fed-Ex or UPS and need a signature upon delivery. USPS International First Class shipments may take four to five weeks to be delivered. USPS International Priority shipments may take two to three weeks. 

International shipping usually takes seven to 21 working days but may take up to six weeks in some cases. Air shipments take up to four to five days, apart from customs processing time. Delivery may take up to two weeks. 

You can return unopened items within 30 days for a full refund of your purchase price, barring shipping charges or any discount. Opened items can be returned within 30 days for a partial refund, which will be the price of the smallest unit available for that product. 

Customer service is available seven days a week from 7.30 am to 4 pm through live chat, phone, and email. 


Ingredients: 500 mg of berberine HCl (bark) per serving. 

Dosage: Take 500 mg (about 1/5th teaspoon) once or twice daily or as directed by a physician. 

Pack sizes: 25 grams (0.9 oz), 50 grams (1.8 oz), 100 grams (3.5 oz), 250 grams (8.8 oz), 500 grams (1.1 lbs.), 1 kg (2.2 lbs.), 5 kg (11 lbs.), and 25 kg (55 lbs.) 


  • Pure, raw ingredients 

  • No additives, flavorings, or fillers 

  • FDA-inspected manufacturing facility 

  • Follows cGMP 

  • In-house lab-tested for purity (COAs are available upon request) 

  • Free of sugar, soy, dairy, yeast, and gluten 

  • Customer service is available seven days a week 

  • International shipping available 

  • Great customer reviews 

  • 100% refund (minus shipping and postage charges) on unopened items within 30 days of purchase 

  • The company is available seven days a week from 7.30 am to 4.00 pm PST on live chat, phone, and email. 


  • Shipping is not free unless the order is over $49 within the mainland US 

  • According to some customers, the powder tastes bitter 

  • No 100% satisfaction guarantee, i.e., an only partial refund on opened items 

⇒ Visit the Official Website of Berberine HCL 

#2. Berberine Glucose Support: Most Popular Berberine For Weight Loss 


Sunergetic is an herbal supplement manufacturing company that has been doing good business for over five years. All supplements are formulated with high-quality herbs, sourced from around the world. 

The company sources its berberine from Berberis aristata, one of the key berberine resources in nature. The company’s supplements are manufactured in an FDA-registered facility that adheres to cGMP. You can buy the products from the brand website as well as Amazon. But we would recommend you purchase directly from the company website to get the maximum benefit.  

Even though the price of this product is a tad bit higher than the first brand we’ve mentioned, this brand offers 100% satisfaction to its customers. This product comes in capsule form, with each capsule containing 600mg of Berberine HCI. Since the capsule shells aren’t made from animal gelatin, anyone can have them.  

Standard shipping takes about three to five business days within the US. It also offers two-day expedited shipping for $15 and one-day Priority Shipping for $20 within the US. The company ships internationally, too. 

Sunergetic offers a 365-day satisfaction guarantee. If you are not happy with your purchase, you can send an email to [email protected] and get a refund on the most recent purchase, no questions asked. 


Ingredients: 600 mg of berberine HCl per capsule, 1200 mg per serving 

Dosage: Take two pills per day with meals or as directed by a doctor; each bottle contains 60 capsules, i.e., enough to last a month. 


  • Premium ingredients 

  • Vegetarian capsules 

  • Free of yeast, corn, preservatives, dairy, and soy 

  • Manufactured in an FDA-registered facility 

  • Adheres to cGMP 

  • 365-day satisfaction (unconditional 100% money-back) guarantee 

  • Available on Amazon as well 


  • Free shipping only on orders above $40 

  • May not be gluten-free since a customer allergic to gluten got sick 

⇒ Visit the Official Website of Berberine Glucose 

#3. Berberine Root Extract: Highly Trusted For People With Lower Sugar Levels 

Berberine Root Extract
Berberine Root Extract

Established in 1973, Solaray has not only been providing customers with the best supplements for optimal health but also making the planet a better place for everybody. 

This product is also available in capsule form, with capsule shells made from vegan ingredients. The brand draws its berberine from Indian barberry with Oregon grape.  

Its bottles are 100% post-consumer recycled plastic, and every bottle has a slight variation in color because of that. Many of its products are organic. 

Orders over $50 are eligible for free delivery. There is no overnight shipping, but you can expect your shipment to arrive within three to five business days. Solaray supplements can be found at your local health food store or on various online stores, including Amazon, apart from the brand’s own site. 

If you are not satisfied with any item, you can place a request for a refund or replacement product within 60 days. 


Ingredients: 250 mg of berberine HCl (root extract from Indian barberry) and 285 mg of Oregon grape root. 

Dosage: One capsule with a meal or a glass of water. Each bottle contains 60 capsules. 


  • Lab-verified 

  • Vegan 

  • Non-GMO 

  • Environment-friendly practices 

  • 60-day satisfaction (money-back) guarantee 


  • Only orders above $50 are eligible for free delivery 

  • Limited shipping options 

⇒ Visit the Official Website of Berberine Root 

#4. Berberine-500: Recommended Berberine Supplements For Better Heart Health 

Berberine 500
Berberine 500

As a health products manufacturer, Thorne promotes healthy living. Apart from selling a large number of supplements, it also offers test kits. 

Its berberine supplements are free of gluten, dairy, and soy. As part of its commitment to its customers, it clearly indicates that pregnant or breastfeeding women should refrain from its use. It also makes consumers aware of berberine’s tendency to interfere with certain medications owing to its interactions with some liver enzymes. 

All retail orders within the US, except Alaska and Hawaii, enjoy free ground shipping. Expedited shipping is available on request but for a fee. International shipping is also available, but it may take up to four to six weeks to be delivered. 

If you are not satisfied with a product, you can return it within 60 days to get your money back, earn store credit, or get a replacement. Another great thing about Thorne is that all its packing and shipping materials are made from recycled stuff. 


Ingredients: Total 1 gram of berberine HCl (root), calcium laurate, and Hypromellose capsule 

Dosage: Take one or two capsules twice daily or as recommended by your doctor. Each bottle contains 60 capsules. 


  • Natural flavors and colors 

  • Gluten-free 

  • Dairy-free 

  • Soy-free 

  • Environment-friendly practices 

  • Great customer reviews 

  • Free ground shipping in the US (except Alaska and Hawaii) 

  • Expedited shipping is available for a fee. 

  • International shipping is available 

  • 60-day money-back guarantee 


  • International shipping is slow 

  • International sales are final, i.e., no returns, irrespective of the time elapsed since purchase 

⇒ Visit the Official Website of Berberine-500 

#5. Berberine Pure+ : Best Supplement For Lowering Cholesterol Levels 

Berberine Pure+
Berberine Pure+

Nuzena is a natural supplement company dedicated to improving health and wellness. It offers a line of natural supplements that are tested both in-house and by third-party labs for safety, quality, and effectiveness. 

This product, being made from natural ingredients, is specially tested for microbes, allergens, and heavy metals that are commonly found in soil.  

It has a team of registered dietitians, food scientists, and nutritionists to provide customers with a free consultation and comprehensive health and wellness report. This report includes personalized nutritional and lifestyle advice and resources and tools to implement that advice. 

The products are made from pure and all-natural ingredients within an FDA-registered facility, which strictly follows GMP regulations.  

Standard USPS delivery time within the US is three to five business days, and it’s free. Two-day USPS delivery takes two business days for a flat rate of $9.95. DHL International takes seven to ten business days for delivery for a flat rate of $14.95. 

To be eligible for a return, your item must be unused and in the original packaging, in the same condition that you received it. 


Ingredients: 1200 mg of Berberine HCl (and vegetable cellulose for capsule shells) 

Dosage: Take two capsules daily. For the best results, take two capsules 20 to 30 minutes before a meal or as directed by your doctor. There are 60 capsules in every bottle. That should last you for a month. 


  • Made with sustainably sourced, pure, and natural extracts 

  • Non-GMO, organic ingredients 

  • Clinically proven, gluten-free ingredients 

  • In-house and third-party lab-tested 

  • Vegan capsules 

  • Sugar-free  

  • Made in an FDA-registered facility in the US 

  • Simple and easy returns 

  • Free personal health specialist consultation included with purchases 


  • No satisfaction guarantee 

  • Free shipping only on purchases worth more than $50 

⇒ Visit the Official Website of Berberine Pure 

How We Made The List Of Top Berberine Supplements? 

With the amazing properties of berberine being discovered, many companies have come up with supplements containing the compound. However, since the herbal supplement market is also full of phonies and fakes, we had to be careful about what we picked.  

We conducted thorough research, surveys, and spoke to various companies, industry experts, and common consumers to be sure about the veracity of companies, the performance of the products, and the services provided by the companies doing business in berberine supplements.  

While doing our research, we looked into various factors to be sure we could find the best in the market. And here are the factors we looked into: 

  • Ingredients 

Ingredients are critical to any supplement’s composition. Apart from the formulation, which is definitely important, ingredients define what goes into the product and whether or not the supplement will benefit you.  

We made sure that the supplements contained nothing but berberine in its purest form. If it’s a pill, the coating, of course, is also an essential factor.  

HCl or hydrochloride is often added to help with digestion since the compound can cause digestion issues.  

We selected brands that used organic berberine (since it’s an herbal compound) and those which follow all good manufacturing practices and regulations, in addition to making their supplements in FDA-registered facilities following cGMP standards.  

No product containing artificial colors, flavors, or any other additive made its way to this list.  

We also checked the weight of the compound to make sure that you get a healthy dose of the compound. A low dose may be ineffective, while a very high dose could be harmful in the long run. Our chosen brands satisfied all our criteria comfortably.   

  • Lab testing 

We have given priority to supplements tested by state-licensed third-party labs.  

Though most supplement-manufacturing brands do not mention lab reports and lab tests, it’s best to buy those which are tested for safety and efficacy. Even though third-party lab tests are the best parameter in this regard, even an in-house lab test is better than no lab test.  

Since supplements do not usually have an FDA seal-of-efficacy label, you have to rely solely on research studies, lab reports, and ingredients mentioned by the company and the lab that tested the products.  

Always opt for supplements that have ample portions of the essential compounds in their purest form. In such cases, lab test reports are your only seal of purity. 

  • Customer Reviews 

One of the best ways to make sure that we get the best product is by diligently going through customer reviews.  

All our chosen supplements have high ratings and have received largely positive testimonials from customers.  

If any customer has had a negative experience with any product or the company’s services, we have listed that too, so that you can make an informed decision. Most people seem to have benefited from using these products. 

  • Shipping, Returns, and Packaging 

When it comes to online shopping, only choosing the best product or brand is not enough. You have to take a look at the customer policies too. We made sure that the brands we suggest offer easy and convenient shipping and returns policies.  

If there is anything negative about these policies, we have pointed that out for your convenience.  

Some of the brands even offer satisfaction guarantees that allow you to claim a refund if you did not get the desired results after using the product you bought.  

Besides, we also looked into the level of commitment and care put in by the company while sending the packages. If the packaging is good, it shows that the company cares enough to ensure the product reaches you safely, and you can keep using it every day without having to worry about changing the container as long as the product remains. In other words, the companies who care about their customers’ expectations and satisfaction send their packages in good condition, contained in solid packages. 

Needless to say, it’s best to buy from brands that care enough about their customers to serve them best. Their policies highlight their confidence in their products and their commitment to serve in the long run. 

Berberine Weight Loss Reviews Guide 

Though we have listed what we believe to be the five best berberine supplements on the online market, you may want to do some research on your own. You got the right to do that. However, since the market is teeming with bogus products, we suggest you follow this buying guide that we have devised for you. 

  • Consult A Doctor (Don’t self medicate) 

First and most importantly, do consult a doctor before starting a berberine supplement. It’s a wonderful compound, no doubt, but it also has side effects and negative effects in the long term. So, only a doctor can guide you on the proper dosage and the duration of consumption. We have mentioned some of the side effects and toxicities of berberine in our FAQs section. Take a look at those and be careful not to invite any trouble into your life. Also, you must make sure that you need the berberine supplement. Do not jump into it just because your friend is taking it and is benefiting in some way. It may have no use for you. 

  • Check The Ingredients (They hold the key to its efficacy) 

Take a good look at the ingredients used in the supplement of your choice. Check how much of the compound each pill contains. The safe consumption limit for berberine is up to 1.5 grams per day. DO NOT exceed it at any cost. Follow the dosage mentioned on the label or prescribed by your doctor to the T. Also, when you buy a supplement, make sure that it contains nothing but the berberine compound in its pure and natural form.  

Many supplements contain HCl (hydrochloride) for better digestion. It’s important because berberine can disrupt the digestion process. If you see any other ingredient apart from these and the pill coating, check what it is. It may be a filler. Stay away from such products even if they are given away for free. Also, buy supplements with no artificial additives, such as colors, flavors, or sweeteners. Yes, berberine has an abominable taste. But stay away from sugar coatings, especially if you are taking it for diabetes!   

  • Look For Lab Certification (Do check the reports carefully) 

Supplements are not approved by the FDA as a medication or a cure for any ailment. Hence, they do not enjoy the FDA’s watch. So, how would you know whether what you are getting is the real deal or not? That is where certification from a good and reputable lab plays a key role. The best brands get their products tested by third-party labs as the ultimate proof of authenticity. Some big brands rely on their in-house labs. But any certification is a mark of safety and genuineness. So, always look for mentions of lab tests. If necessary, ask customer service about it and request to see the lab report. If they refuse to share it with you or behave rudely, it is better to avoid that site like the plague.   

  • Check Customer Feedback (Don’t be naive and rely on a company’s promises blindly) 

It is extremely important to check the reviews left by past customers no matter what claims the brand has made about its products. It is not enough to read the positive comments. Take your time to go through the entire list and read the negative remarks too. See if anybody has experienced any side effects or has mentioned any shipping issues or bitter experiences while shopping. How the brand resolved the issue can also be very telling. Make 100% sure about the brand and the product before making the payment. 

  • Check the brand’s customer policies (You may want to return it if it doesn’t work for you) 

Look for companies that offer a money-back guarantee. These are usually the most confident about their products, and confidence comes from quality. Even though we sincerely hope that you do not have to return the product and claim a refund, these promises assure you that your money won’t go down the drain. Also, read the brand’s shipping and return policies carefully. If the shipping cost is more than the product cost, it won’t make any sense to buy it, right? Some companies do not even take any responsibility for products lost in transition or undelivered products. Trust them at your own risk. 

FAQs On Berberine Supplements  

Q1: What is berberine? 

A: Berberine is a yellow-colored chemical found in plants such as European barberry, goldenseal, goldthread, Oregon grape, Phellodendron, and tree turmeric (Indian barberry or Daruharidra). It has been used in traditional Indian and Chinese medicines for hundreds of years. 

Berberine is bitter to taste, but it might help strengthen your heartbeat, kill bacteria, help regulate the body’s blood sugar levels, and reduce swelling. Berberine is most commonly used for diabetes, high cholesterol levels, and high blood pressure. 

Often, hydrochloride is added to help with digestion. Berberine can also be applied topically to the skin. It can be used for burns and canker sores. It may help with certain liver diseases, too, but scientific evidence to support many of these uses is lacking. 

Q2: What are the benefits of berberine? 

A: Berberine has a host of benefits. We have listed a few of them. But scientists the world over are still investigating and are expected to find many more.   

The most celebrated use of berberine is in regulating glucose and lipid metabolism in Type 2 diabetes patients. It may lower blood glucose by increasing insulin receptor expression and also support liver health. 

Berberine may also control high cholesterol levels or other fats (lipids) in the blood (hyperlipidemia). It may help lower total cholesterol, low-density lipoprotein (LDL or “bad”) cholesterol, and triglyceride levels in people with high cholesterol. 

In an animal study, berberine was shown to decrease blood pressure and increase vasodilation in diabetic rats. So, it may help hypertension patients, too. 

Berberine has also been shown to have the potential to help with the treatment of prostate cancer. Not only that, berberine may help women with polycystic ovarian syndrome (PCOS), too. It can ease insulin resistance, lower serum androgen levels, regulate lipid metabolism, and control chronic inflammation in PCOS patients. 

In a study, a gel containing berberine was shown to significantly reduce pain, size, redness, and oozing of canker sores. Berberine may also support vision health and bones. And, finally, if all the above details could not impress you, it may even help you lose weight! 

In short, berberine may seem like a wonder drug or superfood, but many of these studies are basic and need further research to back them up. But, undoubtedly, the extract has amazing potential. 

Q3: Does berberine have any side effects? 

A: Yes, berberine is not often easy on the tummy. Some common side effects of berberine include diarrhea, constipation, gas, and an upset stomach. 

Q4: Who should not take berberine? 

A: Pregnant women should not take berberine. It can penetrate the placenta and harm the fetus. Also, if you are breastfeeding, it would be wise to stay away from berberine. It can be transferred to the infant through breast milk and cause harm. 

Berberine should never be given to newborns either. Infants exposed to berberine have been known to have developed kernicterus, a type of brain damage. Berberine may cause brain problems, especially in infants with high levels of bilirubin in the blood, by preventing the liver from removing bilirubin fast enough. 

Q5: Does berberine react with any medications or chemicals? 

A: Yes. One such compound is cyclosporine — a drug used as an immunosuppressant. The body breaks it down to flush it out. However, berberine may slow down that process and cause high levels of cyclosporine in the body. It could potentially cause side effects. 

Similarly, berberine interacts with other medications changed by the liver (cytochrome P450 3A4 [CYP3A4] substrates). These medications are broken down by the liver, but berberine might slow down that process. Apart from cyclosporine, some medications changed by the liver include lovastatin, clarithromycin, indinavir, sildenafil, triazolam, and many others. 

So, if you are taking any medications or have underlying health conditions, do not forget to discuss everything in detail before taking berberine. 

Q6: What is a safe dose of berberine? 

A: Berberine is safe for adults in daily doses of 0.4 to 1.5 grams by mouth for up to two years. Do not take it for long durations because it may have toxic effects on the liver and lungs. 

Conclusion: What Is Berberine Used For & The Best Berberine Supplement Brands? 

Berberine is indeed one of the miracle compounds found in nature. However, it can be likened to nuclear power. It can do wonders; it can also destroy. How you use it is up to you. 

It can help you with several health problems. But it can also cause some if you keep taking it for too long or too much of it. It can also react with certain medications and cause irreversible harm to babies. So, it is important to follow the dosage and also consult a medical practitioner before starting its use. Pregnant and nursing mothers should avoid it completely. 

We have listed some of the best brands that sell effective berberine supplements on the online market right now. Berberine powder is very effective, but it’s extremely bitter. So, if you think you cannot handle that, a pill may be the best option for you. 

Also, it may cause some stomach issues, but you may find that the benefits are greater than the discomfort, which may be temporary. In any case, we recommend that you consult a doctor at once if you face any problems. 

We hope berberine keeps you healthy and leaves no bitter taste in the mouth!  


Disclaimer: The above is a sponsored post, the views expressed are those of the sponsor/author and do not represent the stand and views of Outlook Editorial.