Contrave is a prescription medication that provides bupropion and naltrexone. It's approved by Health Canada as an anti-obesity treatment and is available at all good Canadian pharmacies.
In this article, we are going to explain what Contrave is and how it works and how to get in Canada and what is the typical cost price in CAD$ (Canadian dollars). We are also going to look at the side effects and risks of using Naltrexone-Bupropion to manage body weight.
Due to its drug class and high cost we will look at the cost of using Contrave as well and provide details of other medications and three natural alternatives that are cheaper and safer to use.
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Cheaper and Safer Alternatives to Contrave: A Sneak Peak
What is Contrave?
Contrave is a combination medication specifically designed to provide weight loss support. It contains bupropion and naltrexone.
Bupropion (bupropion hydrochloride) is an antidepressant that's also useful for aiding smoking cessation. Naltrexone (naltrexone hydrochloride) is primarily used to treat alcohol and opioid addiction. naltrexone hydrochloride
Contrave works by targeting the receptors in the brain that are responsible for regulating appetite and reward mechanisms. Bupropion HCL helps to reduce food cravings and increase feelings of fullness, while naltrexone helps to decrease the rewarding effects of food.
By combining these two ingredients, Contrave for weight loss can help people control their calorie intakes, avoid succumbing to cravings, and manage their body weight.
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As with all the other chronic weight management medications approved by Health Canada, Contrave is typically prescribed alongside a comprehensive weight management program that includes a reduced calorie diet and regular physical activity.
However, although Contrave works well for many people, it does not work for everyone. Some people do not respond to the medication, while others have to stop using it due to unpleasant side effects.
It's also worth noting many people who would like to use Contrave cannot do so. It's only available to overweight people with an initial body mass index (BMI) of 30 Kg/m2 or higher.
Health Canada also permits doctors and healthcare professionals to prescribe Contrave to people with an initial body mass index of 27 Kg/m2 or above. However, doctors can only do this for patients with at least one weight-related comorbidity, such as type 2 diabetes or dyslipidemia (abnormal amounts of triglycerides, cholesterol or fat in the blood). healthcare professionals
3 Contrave Alternatives Everyone Needs to Know About
We have already introduced you to these weight loss supplements. Now we will provide brief product overviews that explain what they can do.
#1 - PhenQ
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PhenQ is a popular weight loss supplement that's gained more than 190,000 satisfied customers all over the world. It helps people to become slimmer by targeting multiple aspects of weight loss.
PhenQ is an all-natural supplement that combines several key ingredients, including caffeine, capsicum, chromium picolinate, caffeine and nopal cactus extract. It also provides an exciting proprietary ingredient called a-Lacys Reset.
The PhenQ ingredients work synergistically to provide a range of potential benefits, such as faster metabolism and appetite suppression. These two benefits alone can deliver significant increases in fat burning.
The formulation also increases energy levels and naturally enhances mood.
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PhenQ's multi-dimensional approach sets it apart from those run-of-the-mill weight loss pills that let so many people down. By addressing various aspects of weight loss simultaneously, the supplement provides a comprehensive level of support that helps people to reach their body goals without having to endure unpleasant side effects.
Unfortunately, you can only buy the supplement online, but the manufacturer provides free rapid shipping to all Canadian provinces and territories. Customers placing their first order also get a 60-day money-back guarantee.
#2 - Capsiplex
Capsiplex is a dietary supplement that has gained popularity in the weight loss industry due to its focus on harnessing the potential benefits of capsaicin, the active compound found in chili peppers.
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Capsaicin is well-known for its thermogenic properties and ability to deliver rapid improvements in fat loss. It also controls hunger and provides additional weight management support in other areas.
Capsiplex utilizes a patented chili pepper extract that has a unique beadlet design that releases capsaicin gradually, reducing the likelihood of digestive system irritation or discomfort.
Although Capsiplex was originally only available in one version, there are now two. Capsiplex Burn is specially formulated for men, while Capsiplex Trim is designed for women. The subtle differences between the two formulations reflect this fact.
Unfortunately, you won't be able to find a local Canadian supplier. You can only buy Capsiplex online. However, rapid free shipping comes as standard, and the manufacturer offers a 60-day money-back guarantee.
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#3 - Zotrim
Zotrim is a natural herbal supplement for weight loss. It provides a cutting-edge combination of yerba mate, guarana, and damiana.
These three South-American herbs work in synergy to support weight management by reducing appetite, increasing satiety, and boosting energy levels.
To get the best results from Zotrim, you need to take it before meals. Doing so will help you to control your portion sizes and avoid cravings that may otherwise cause you to snack.
By curbing excessive food intake and providing an energy boost, Zotrim makes the weight loss process much easier and unlike Contrave, it has no known side effects at all.
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As with the previous two supplements you could use as a substitute for Contrave, you can only buy Zotrim online. However, with free shipping and a 100-day money-back guarantee, Zotrim provides excellent value for money.
Contrave Suitability and Interaction Issues
Contrave is a prescription medication intended for people dealing with obesity or excessive weight who have failed to make any progress to lose weight by following a reduced calorie diet and increasing their activity levels.
However, Contrave may not be suitable for everyone. There are certain contraindications and precautions to consider.
Contrave is unsuitable for people suffering from uncontrolled hypertension (high blood pressure). It's also a poor choice for people suffering from seizure disorders or people with a history of seizures or eating disorders such as anorexia nervosa or bulimia.
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Nor is Contrave an appropriate choice for anyone who is taking opioids or has a history of opioid dependence. It's also not recommended for people undergoing abrupt discontinuation of alcohol, benzodiazepines, barbiturates, or antiepileptic drugs.
Additionally, women who are pregnant, planning to become pregnant, or currently breastfeeding should not use Contrave.
Contrave can also present interaction issues if it's used alongside certain medications.
Examples of medications that may interact with Contrave include monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants, antipsychotics, opioid medications, and blood pressure medications.
If your doctor offers to prescribe you Contrave, it's important to be certain they are aware of your complete medical history so they can assess the potential risks and benefits and determine if Contrave is suitable for you.
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You will also need to provide information about any medicines or supplements you have obtained from an alternative source, such as a dental practitioner. This type of full disclosure will help your doctor to make certain Contrave is an appropriate choice.
Contrave Efficacy and Clinical Trials
Contrave's safety and efficacy have been explored in several clinical trials.
Here is an overview of some key clinical trials of Contrave:
COR-I (Contrave Obesity Research I) Trial
This trial included obese or overweight individuals with at least one weight related comorbidity. The participants were randomly assigned to receive Contrave or a placebo along with a reduced-calorie diet and increased physical activity.
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Data from the study shows using Contrave, in combination with appropriate lifestyle modifications, led to greater weight reductions (compared to a placebo).
The most common side effect was nausea. Reports of headaches, dry mouth, dizziness, and vomiting were also quite common. [1]
COR-II (Contrave Obesity Research II) Trial
This trial aimed to assess the long-term efficacy and safety of using Contrave for weight management. It included individuals who had completed the COR-I trial and continued using Contrave or a placebo for an additional 56 weeks.
The results showed sustained weight loss in the Contrave group (compared to the placebo group). As with the previous trial, nausea was the most common side effect. [2]
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These trials, among others, have contributed to the evidence supporting the use of Contrave as a weight loss medication. They confirm using Contrave, in conjunction with lifestyle modifications, can lead to significant weight loss and improvements in metabolic health markers.
However, although clinical trials provide valuable information, individual results may vary. The effectiveness and safety of Contrave may depend on factors such as the user's overall health and adherence to the lifestyle changes that are necessary to create the energy shortage that forces the body to burn its stores of fat for fuel.
Contrave Side Effects and Health Risks
Like any medication, Contrave can cause side effects. Some users may not experience any side effects at all, but many do.
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Common side effects may include:
- Nausea
- Headache
- Constipation
- Dizziness
- Insomnia
In addition to these common side effects, Contrave also has the potential to cause additional health risks.
Increased Blood Pressure
Contrave can raise blood pressure levels. People who have pre-existing hypertension or cardiovascular conditions will need to show extra caution before and while using Contrave.
Seizures
There is a small risk of seizures associated with Contrave. The risks are greater for people who are already prone to seizures or have certain medical conditions that increase the likelihood of them.
Mood Changes and Suicidal Thoughts
Contrave contains bupropion. This antidepressant medication can increase the risk of mood changes and suicidal thoughts. People with a history of depression or psychiatric disorders are more likely to fall victim to these rare Contrave side effects.
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If you experience any side effects while using Contrave, it's important to let your doctor know about them.
A Look at the Cost of Using Contrave
The average cost of using Contrave in Canada can vary depending on several factors, including the location, dosage, duration of treatment, and individual insurance coverage.
If you are considering using Contrave, it's important to be aware the price can change over time. With this in mind, we suggest you get up-to-date price information by checking with your local pharmacies.
Typically, the cost per month can range from approximately $100 to $300 or more. However, it's important to keep in mind that this is just a general estimate. Various factors can affect the overall costs.
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Some insurance plans may provide partial or full coverage for Contrave. Others may not cover it at all. Checking with your insurance provider or consulting with a pharmacist can provide clarity on coverage options and any copayments or deductibles that may apply.
Additionally, some suppliers may offer savings programs or discount cards that can help reduce the out-of-pocket cost for eligible people.
Contrave and Health Insurance: What You Need to Know
Most Canadians who have private medical insurance should be able to get help paying for Contrave. The best way to learn if your insurance covers you for using Contrave is to check your policy details or contact your insurance company.
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Insurance coverage for Contrave may be full or partial. If your insurance company only provides partial coverage, you may have to pay a percentage of the overall monthly usage costs out of your own pocket.
Where to Buy Contrave in Canada
1. Shoppers Drug Mart: One of the largest pharmacy chains in Canada, with locations in most major cities. They offer a wide range of medications and health products.
2. Rexall: Another major pharmacy chain in Canada, with over 400 locations across the country. They offer prescription medications, over-the-counter drugs, and health services.
3. London Drugs: A Western Canadian pharmacy chain that also sells electronics, furniture, and other products. They offer prescription medications and health products.
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4. Pharmasave: A network of independently owned pharmacies across Canada. They offer prescription medications, health products, and services such as flu shots and medication reviews.
5. Jean Coutu: A Quebec-based pharmacy chain with over 400 locations across Canada. They offer prescription medications, health products, and services such as blood pressure monitoring and medication reviews.
6. Uniprix: A Quebec-based pharmacy chain with over 300 locations across Canada. They offer prescription medications, health products, and services such as flu shots and medication reviews.
7. Familiprix: Another Quebec-based pharmacy chain with over 400 locations across Canada. They offer prescription medications, health products, and services such as medication reviews and home health care products.
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8. Guardian: A Canadian pharmacy chain with locations in Ontario, Manitoba, and Saskatchewan. They offer prescription medications, health products, and services such as medication reviews and compounding.
9. IDA: A Canadian pharmacy chain with locations across the country. They offer prescription medications, health products, and services such as medication reviews and home health care products.
10. Remedy'sRx: A Canadian pharmacy chain with over 150 locations across the country. They offer prescription medications, health products, and services such as medication reviews and blood pressure monitoring.
It's important to note that Contrave is a prescription medication that requires a prescription from a licensed healthcare provider. The availability and pricing of Contrave may vary depending on the pharmacy and location. It's recommended to check with individual pharmacies for specific pricing and availability information.
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Cheapest Contrave Price in Canada
Contrave is available in tablet form consisting of 8 mg naltrexone hydrochloride and 90 mg bupropion hydrochloride. The recommended dose for Naltrexone-Bupropion is two tablets twice daily. At the submitted price of CAD $2.21 per tablet. The cost per year to buy Contrave from a Canadian pharmacy is CAD $3,234.
Contrave (Naltrexone-Bupropion) FAQ
How effective is Contrave for weight loss?
Data from Clinical trials show Contrave can work well alongside diet and exercise.
However, individual results may vary. Some people who have experience using this medication complain it did not help them at all.
Can anyone use Contrave?
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No. Before prescribing you Contrave, your healthcare provider will assess your medical history and determine if Contrave is appropriate for you.
How long can you continue taking Contrave?
The duration of Contrave treatment can vary depending on individual needs and body goals. If the treatment is successful, you will not be able to continue using Contrave after your body weight becomes lower than the BMI threshold that permits your doctor to prescribe it.
Your doctor will determine the appropriate duration and may recommend adjustments or discontinuation based on your progress and overall health.
Contrave Research Sources 2023
Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomized, double-blind, placebo-controlled, phase 3 trial: https://pubmed.ncbi.nlm.nih.gov/20673995/
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A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity-related risk factors (COR-II): https://pubmed.ncbi.nlm.nih.gov/23408728/
Disclaimer: The above is a sponsored post, the views expressed are those of the sponsor/author and do not represent the stand and views of Outlook Editorial.
