Alpilean Reviews: Claims, Contradiction & Conclusions In 2023

Over 30% of adults are obese, and 65% are overweight in the United States. The scenario makes it a growing public health concern.

A low internal body temperature is one of the primary causes of obesity. However, ALpilean has an answer for this!

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Alpilean helps with weight loss by raising and maintaining the inner body temperature within the normal range by combining seven potent natural ingredients. Besides, the supplement does not contain any hepatotoxic substances like ephedra.

The effects make it an excellent choice for anyone looking to improve their health.

However, like any other weight loss supplement Alpilean has some scientifically proven outcomes and contradictory claims. We will review almost all the user experiences and available scientific evidence to compare those claims and contradictions.

What is Alpilean?

Alpilean is a weight loss supplement that uses several natural ingredients from the Alps that increase your core body temperature and boost metabolism. It is made by Zach Miller, Drs Matthew Gibbs, Palta, Anders, and Lubanzi.

Alpilean

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Alpilean is a vegetarian, non-GMO, and soy-free weight loss supplement that suits almost anyone. However, some reviews have raised questions about its effectiveness and safety.

Alpilean Benefits

According to some sources, Alpilean may have benefits such as:

●   Rapid fat burning by raising your inner body temperature
●   Blood pressure regulation, improved digestion, and joint health
●   Suppressing hunger and promoting long-term weight loss
●   Working even when you are sleeping

Alpilean Side Effects

Alpilean has no major or serious side effects because it is mostly made of natural substances. However, a few studies and reviews claimed that there might be some negative side effects such as

●   Overstimulation, jitteriness, or insomnia
●   Allergic reactions to some ingredients
●   Interactions with medications or health conditions

Alpilean Reviews: Claims vs Contradictions

Alpilean contains seven natural ingredients and vitamin B12 that are claimed to have weight loss effects through thermogenesis. However, we have found some contradictory findings, especially about Dika Nut, Bigarade Orange, and Chromium Picolinate.

Ingredients	Claim	Contradictions
*Fucoxanthin*	Thermogenetic effect on white adipose tissue leading to fat cell burning.	No contradictions.
*Dika Nut*	Thermogenic effect on white adipose tissue leading to fat cell burning.	No proven thermogenic effect on adipose tissues. On the contrary, it reduces the effect.
*Ginger Rhizome*	Thermogenic effect on white adipose tissue leading to fat cell burning.	No contradictions.
*Moringa Oleifera*	Thermogenic effect on white adipose tissue leading to fat cell burning. Advertisement	No contradictions.
*Bigarade Orange*	Thermogenic effect on white adipose tissue leading to fat cell burning.	Combination effect of thermogenesis, appetite suppression, and insulin system.
*Curcuma Longa*	Thermogenic effect on white adipose tissue leading to fat cell burning.	No contradictions.
*Chromium Picolinate*	Weight loss is associated with insulin resistance.	Only work on type 2 diabetes patients who are taking other medications.

Some of the ingredients of Alpilean may not have the desired effect as described on the containers; however, the combined effects of those natural and highly potent ingredients can significantly help you to shed some extra weight.

Moreover, the drug contains no substances that are either banned or not recommended for their hepatotoxic effects. So you can be sure about your safety while taking the supplement.

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How Does Inner Core Body Temperature Impacts Fat Loss?

Increasing your inner core body temperature can boost your metabolism and fat burning by activating a type of fat called brown fat stored in the brown adipocyte cells.

However, a little research didn't find clear evidence between raising the core temperature and weight loss. Other factors may affect body temperature, weight, and subsequent metabolism. The factors include genetics, hormones, diet, exercise, and environmental conditions.

How Long Does It Take to Show Results with Alpilean?

The results of Alpilean may vary from person to person, depending on their

●   Body type
●   Metabolism
●   Lifestyle, and other factors

Alpilean will take around 3 to 6 months to show ideal results. This is because losing weight is not a fast process; it takes time to normalize the inner body temperature.

However, some people may notice observable results in as little as a month if they use one capsule daily with a glass of water.

Alpilean Weight Loss Reviews: Ingredients That Cause Weight Loss Scientifically

Let’s look at the seven ingredients of Alpilean that claim to burn fat through thermogenesis. We have researched the ingredients' effects, outcomes, and possible side effects to give you a clear overview of the supplement.

Fucoxanthin

Fucoxanthin is a safe and natural marine carotenoid that can help you achieve your weight loss goals by promoting thermogenesis and fat oxidation.

The carotenoid is a natural ingredient extracted from a type of seaweed called Undaria. This natural ingredient helps with weight loss by increasing the heat produced in fat tissue through thermogenesis and is crucial for limiting weight gain and promoting weight loss.

Fucoxanthin stimulates the expression of a protein called UCP-1, which releases chemical energy as heat. This UCP-1 protein is usually found in brown adipose tissue, but fucoxanthin can also induce its expression in white adipose tissue.

By doing so, Fucoxanthin promotes fatty acid oxidation and heat production in fat tissue, leading to weight loss. This natural marine carotenoid has also been found to increase sensitivity to nerve stimulation, which can further increase fat oxidation.

Studies have shown that mice given a diet with 0.2% fucoxanthin had significantly attenuated weight gain.

Dika Nut

The Dika Nut (Irvingia gabonensis) seeds contain a lot of soluble fiber. This fiber can help your body absorb sugar more slowly and prevent forming of new fat cells adipocytes. The high fiber content of the seed competes with cholesterol and helps to remove it.

It can also act as a natural laxative and help keep your digestive system healthy.

However, no studies have found the thermogenesis effect of Irvingia gabonensis extract on fat cells claimed by the Aplilean. Dika nut extract, contrarily, reduces serum Leptin levels that regulate thermogenesis at the cellular level.

People who took this supplement showed significant decreases in body fat percentage and waist circumference. Additionally, it was found to improve total cholesterol, LDL, and fasting blood glucose levels . These improvements can help decrease the overall health risk for people who are overweight or obese and at risk for metabolic syndrome.

So, taking Irvingia gabonensis as part of a weight loss program can be a beneficial step towards better health.

Ginger Rhizome

Ginger root extract is a natural and powerful weight loss aid with minimal side effects. By incorporating ginger into your diet, you may experience a reduction in body weight, waist-to-hip ratio, heart rate, fasting glucose, insulin resistance, and an increase in good HDL cholesterol . However, ginger doesn't affect insulin levels, BMI, or other cholesterol levels.

One of the great things about ginger is that it can help you lose weight without inhibiting the body's natural ability to digest fat or affecting essential liver functions. It also has antioxidant and anti-inflammatory properties to support overall health and well-being.

The bioactive compounds 6-gingerol and 6-shogaol are found in ginger, and research has shown that 6-shogaol may have additional benefits in terms of its anti-emetic, anti-cancer, and antioxidant properties.

While a recent study on lab rats showed that 6-paradol of a species of the ginger family, Zingiberaceae, can increase the temperature of brown adipose tissue (which is associated with weight loss), no such results have been found in human experiments.

Alpilean claims that the ginger root in the capsules raises the temperature of the adipose tissue and burns fat. However, there is minimal scientific data to support the claim.

Incorporating ginger into your active and healthy lifestyle can be an excellent addition to your weight loss routine. With its natural properties, minimal side effects, and potential health benefits, ginger can be a valuable tool in your journey towards a healthier weight.

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Moringa Oleifera

Moringa peregrina leaf extract has impressive anti-obesity and liver-protective properties. In High-fat diet-induced obese rats, the extract has been shown to increase insulin sensitivity, reduce lipid absorption, lower hyperlipidemia, and provide antioxidant effects to the liver.

One of the ways that Moringa peregrina leaf extract supports weight loss is by potentially modulating the activity of the hormone leptin. The extract may trigger thermogenesis (i.e., heat production) in brown adipocytes at the mitochondrial level by modulating leptin expression, such as PPARγ.

How Moringa peregrina leaf extract provides anti-obesity and other health benefits is not fully understood. However, it's believed that its high levels of various constituents, such as phenolics, carotenoids, flavonoids, tannins, glycosides, vitamins, sterols, minerals, amino acids, and alkaloids, contribute to those therapeutic effects. These constituents are known for their hypoglycemic, hypolipidemic, anti-inflammatory, and antioxidant properties.

Incorporating Moringa peregrina leaf extract into your active and healthy lifestyle could be a game-changer for your weight loss journey. With its powerful anti-obesity and liver-protective properties, this extract could be a valuable addition to your daily routine.

Bigarade Orange

Some weight loss supplements contain Bigarade Orange (Citrus aurantium), which is marketed as a safe alternative to ephedra.

Studies show enhanced weight loss and increased metabolic rate while consuming Citrus aurantium with food. The therapeutic effect is believed to be the combination of thermogenesis, appetite suppression, and impact on the insulin system.

However, Bigarade Orange may also adversely affect health. It contains synephrine, a chemical similar in structure to epinephrine , which can increase blood pressure and potentially lead to heart problems.

The fruit contains 6′,7′-dihydroxybergamottin, and bergapten, which can affect the levels of many drugs in the body. There isn't much evidence that products containing Bigarade Orange help with weight loss, and the lipolytic effects of synephrine on human fat cells are only observed at high doses.

Octopamine, another chemical found in Bigarade Orange, does not similarly affect fat cells.

Curcuma Longa

Curcumin is a natural compound with several potential health benefits. It works in various ways and can affect how cells function in the body.

Researchers found that regular curcumin intake led to the development of beige adipocytes in white adipose tissues in lab mice . The outcome is associated with increased energy expenditure and heat production at the cellular level. Curcumin increased the expression of β3AR genes and norepinephrine hormones, in this case, that promote fat-burning.

Another study on lab mice showed that curcumin reduced inflammation in white adipose tissue responsible for weight gain. The consumption also increased energy expenditure in response to cold temperatures. Scientists found a close association between the temperature rise with increased UCP1 expression in the brown adipose tissue leading to fat burning.

Curcumin is generally considered safe. Still, the World Health Organization recommends a maximum daily intake of 0-3 mg per kilogram of body weight . The European Food Safety Authority has also set a limit for the amount of curcumin that can be added to food, ranging from 20 to 500 mg per kilogram.

Chromium Picolinate

Chromium picolinate may help with weight loss, especially in people who carry excess weight around their midsection. The key factor for this supplement to work is insulin resistance.

In a recent study, individuals with type 2 diabetes taking sulfonylurea medications showed improved insulin sensitivity and glucose control and reduced body weight and belly fat when taking chromium picolinate.

Other studies have also shown slight weight loss with this supplement. However, whether taking chromium picolinate affects how much energy you consume or burn off is unclear.

Some studies suggest that taking chromium may help reduce body fat and increase lean body mass, which could lead to weight loss in humans. However, the evidence is not entirely clear, and the effects may depend on factors such as

●   A person's diet
●   How much chromium they take, and
●   How long they take it

Animal studies support the idea that chromium can affect body composition, but more research is needed to understand how it works in humans fully. So far, there have been no reported harmful effects of chromium supplements in nutritional studies.

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Is Alpilean Legit or Fake?

Aplilena is not fake, and it's legit. This non-GMO supplement is all made in the USA within an FDA-registered facility. You will find only the natural ingredients in this GMP-certified weight loss pill.

However, remember that the FDA does not verify the nutrition information. Thus, you should not consider Alpilean to diagnose, treat, cure, or prevent diseases.

How Much Weight Can You Lose on Alpilean?

The amount of weight you can lose on Alpilean may vary depending on your health conditions and lifestyle. According to one source,

●   1 bottle can help you lose one to ten pounds
●   3 bottles for 11 to 30 pounds, and
●   6 bottles for 30 pounds or more

Another source claims that you can expect to lose a minimum of 15-20 pounds within 3-4 weeks if you follow the dosage instructions and a healthy lifestyle.

Who Should Not Use Alpilean?

Alpilean is a natural product, but it is not suitable for everyone. Some sources say Alpilean is not recommended for underage people or pregnant and breastfeeding mothers. If you have a medical condition or are taking any medication, consult your doctor before using Alpilean or any other weight loss product.

What Are Some Ways To Lose Weight Faster With Alpilean?

Alpilean can help promote weight loss and accelerate fat-burning by increasing your metabolic rate and suppressing your appetite with alpine nutrients. However, to gain the most out of the supplement and achieve faster results, you may also want to follow some lifestyle changes such as:

●   Eating a balanced diet that is rich in protein, fiber, healthy fats, and antioxidants
●   Drinking plenty of water to stay hydrated and flush out toxins
●   Avoiding processed foods, added sugars, alcohol, and caffeine that can interfere with your metabolism
●   Exercising for at least 30 minutes per day and aiming for a mix of cardio and strength training

You may also want to check out the Alpine Ice Hack guide that comes with Alpilean. It is a bonus product that provides information on losing weight quickly by following a specific diet plan and exercise regimen.

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Where Can I Buy Alpilean?

Alpilean is available online from its official website. You can choose from different packages and get discounts and bonuses depending on how many bottles you buy. The prices range from $39 to $59 per bottle, plus shipping charges.

However, before you buy Alpilean, you may want to consult your doctor and go over this review to research its ingredients, benefits, and side effects.

Hepatotoxic Substances Found In Weight Loss Supplements (But Not in Alpilean)

There are at least five substances in regular weight loss supplements, such as Hydroxycut and OEP, that can cause severe hepatotoxicity and consequent liver damage. However, Alpilean does not contain any of them.

Camellia Sinensis (EGCG)

Green tea extract comes from the Camellia sinensis plant and contains polyphenols, which include catechins and flavanols. Popular findings say that catechins have antioxidant benefits. However, they may cause damage to cell membranes and induce the formation of reactive oxygen species, leading to cell death.

The primary catechin in green tea extract, epigallocatechin gallate (EGCG), is associated with liver damage in a dose-dependent manner.

Studies on mice show that high doses of EGCG can cause moderate to severe liver damage due to enhanced oxidative stress.

Additionally, research on dogs has shown that catechins have a higher risk of causing toxicity if taken on an empty stomach. People taking catechin-containing products often fast during weight loss, which may increase the risk of toxicity.

Garcinia Cambogia

Garcinia Cambogia, commonly known as brindle berry or Malabar tamarind, is a common fruit in Asia and Africa. The fruit contains hydroxycitric acid (HCA), which can stop the body from converting carbohydrates into fat. So HCA is often added to weight loss products.

However, the hepatotoxicity of Garcinia Cambogia is not demonstrated yet. Some studies found it could cause liver damage by triggering liver fibrosis, inflammation, and oxidative stress.

Usnic Acid
Popular findings say usnic acid is vital in fat burning. So no wonder it will be included in several weight loss supplements. The acid inhibits the production of reactive oxygen species by preventing mitochondrial oxidative phosphorylation.

However, oxidative stress is suspected to be the main contributor to the development of usnic acid-induced hepatotoxicity.

Ma Huang (Ephedra)

Ephedra alkaloid, also called Ma Huang, is widely used as a dietary supplement for slimming down in the USA. It has been related to multiple incidences of liver failure and is known to impact the cardiovascular and central nervous systems negatively.

Due to these concerns, the sale of ephedra-containing dietary supplements was outlawed in the United States in April 2004. Despite this, you may still find them in various forms and from various unchecked online sources.

Aegle Marmelos

Aegeline is a substance extracted from the Aegle marmelos plant. It is believed to have an anti-fat effect by causing the breakdown of fat cells. However, it's unclear how this substance can cause liver damage, and no one has been able to prove exactly how it happens.

How Scientists Identify Toxic Components in Weight Loss Supplements

Mass spectrometry is a scientific technique used to analyze bioactive substances, chemical components, and byproducts in body fluids, such as blood, urine, saliva, and bile. This helps researchers understand how these substances affect our bodies and identify potential harmful effects like liver damage.

Scientists have also made advancements in using biomarkers to study drug-induced liver injury, which provides further insights into the toxicological mechanisms and how the body responds to drugs. While these methods have been useful in analyzing traditional medications, herbal and dietary supplements pose unique challenges that currently limit their applicability.

It's important to note that specific populations of patients may be at a higher risk for liver injury from weight loss products. Factors such as body mass index and hormonal imbalances in metabolic syndrome may increase the risk of liver damage.

Additionally, behaviors like fasting while taking products containing green tea extract may also predispose individuals to liver injury, as seen in studies on dogs. Researchers must continue to study the interplay of chemical, host, and behavioral factors to identify potentially harmful ingredients in herbal and dietary supplements.

Alpilean Pros and Cons

Some of the pros of Alpilean are

●   It is 100% natural
●   It does not cause any side effects
●   You do not need any restrictive diets or exercises for Alpilean to work
●   It boosts your energy level and immune system
●   It supports your brain and liver health

Some of the cons of Alpilean are

●   It may take a long time to show results (3 to 6 months)
●   It may not work for everyone depending on their health factors
●   It may be expensive compared to other weight loss products
●   It may not be available in local stores or pharmacies

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Conclusion

This comprehensive Alpilean review will help you understand the claims and contradictions surrounding this supplement. While most users have reported positive results, scientific evidence does not support all the manufacturer's claims.

It’s essential to exercise caution when using Alpilean or any other weight loss supplement. Always consult a healthcare professional before adding any new supplement to your regimen.

There are still many unanswered questions regarding the effectiveness of Alpilean. However, safety is not a big concern like other commercial supplements. As more research is conducted, we hope better to understand the supplement's potential benefits and drawbacks.

Disclaimer: The above is a sponsored post, the views expressed are those of the sponsor/author and do not represent the stand and views of Outlook Editorial.