Next for Gauff could be a rematch against No. 1 Iga Swiatek, who beat the 19-year-old American in last year's final at Roland Garros. Swiatek was scheduled to face Lesia Tsurenko in the fourth round later Monday.
Facing seventh-seeded Ons Jabeur of Tunisia, the unseeded American was broken eight times on Court Philippe Chatrier and lost 6-3, 6-1.