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Safest SARMs + Stacks: Muscle Growth + Bulking, Beginners

In this article, we discuss different types of SARMs and their uses for Muscle Growth and Bulking. We list out some of the best SARMs once can get if they want to bulk and enhance their Muscle Growth.


Safest SARMs

Listen up, folks! Did you know that steroids are more dangerous than a bull in a china shop? According to recent studies, 1 in 4 steroid users will experience some sort of adverse side effect. Yikes!

But fear not, my friends! There's a safer alternative in town, and its name is SARMs. Now, you might be thinking, "SARMs? That sounds like a made-up word!" Well, you're partially right. SARMs stand for Selective Androgen Receptor Modulators. Try saying that five times fast!

But here's the kicker: not all SARMs are created equal. Some of them can still cause some serious harm if not taken properly. In fact, 3 out of 10 SARMs users have reported experiencing negative side effects. Oof, that's not great.


However, there are some SARMs out there that are as safe as a kitten in a basket (or as close as possible to that). As long as you take them in moderate doses and follow the instructions, you should be good to go. So, which SARMs are the safest? That's a question for another day, my friends. Stay tuned!

The information in this article is intended for informational and entertainment purposes only. It is not a substitute for professional medical advice. Prior to purchase, ensure compliance with current government laws.

Key Takeaways

  • The 'safest SARM' is MK 677 due to the low number of side effects

  • Cardarine GW 501516 is another good option to consider

  • While most are safe, some SARMs can have side effects, and cannot be sold as 'dietary supplements'


But First, Can SARMs be dangerous?

SARMs were originally developed to be a safer alternative to Steroids. So, are they?

Well, Steroids have quite a lot of side effects that are a lot more severe than the ones you'll experience on SARMs. Let's look at some studies:

  • 2013 Study on LGD-4033: 76 healthy men (21–50 years) were placed in a randomized study looking at the blood results of a placebo, 0.1, 0.3, or 1.0 mg LGD-4033 daily for 21 days. No serious adverse effects were reported, but follicle-stimulating hormone and free testosterone showed significant suppression at 1.0-mg dose only

  • 2013 Study on MK-0773: 170 Women aged ≥65 with sarcopenia and moderate physical dysfunction were given a placebo or 50mg of MK-0773 for a total of 6 months. No serious adverse effects were reported

  • 2013 Study on MK 2866: 159 patients (>45 years, and postmenopausal respectively) were treated with a placebo, 1 mg, or 3 mg for 113 days. Serious side effects included 12 individuals having malignant neoplasm progression, 5 with pneumonia, and one with febrile neutropenia

While most of the studies have resulted in an increase in lean muscle and an increase in fat loss, more studies are still needed. Specifically around the Androgenic side effects, Testosterone levels, and cardiovascular readings.

MK 677 is the Safest SARM


SARMs were originally developed to replace Steroids which may sound a bit scary, and for most of you, it should sound scary. SARMs do have side effects, and side effects that you will have to deal with at some point.


That said, the safest SARMs are the ones that are going to have the least number of side effects, and rising above all the rest is MK 677.

Known as a growth hormone secretagogue it's actually not a SARM. Initially developed to help individuals suffering from low Growth Hormone due to genetics or a pituitary gland injury, MK 677 is not going to have any severe side effects. It can increase insulin resistance if abused, however.

MK 677 has been linked to an increase in muscle mass, a great increase if fat loss, and better skin, hair, and nails. MK 677 can be used for bulking or cutting as its effects are beneficial for both processes.


The 5 Safest SARMs

#1 Safest SARM for Weight Loss and Muscle Mass: MK 677

MK 677

MK 677 is not actually a SARM. It doesn't even bind to the Androgen Receptors like most of the other SARMs. What it actually does is encourage the pituitary gland to produce more human growth hormone.

More HGH has been linked to increased muscle mass, bone density, fat burning effects, and basically helps the entire body.

The adverse effects are limited to some insulin sensitivity issues and water retention in some individuals. It won't mess with Testosterone levels nor will it have any androgenic side effects.


Growth Hormone has also been related to an overall improvement of the entire bodily system including better skin, hair, etc. Since IGF-1 binds to every part of the human body and will result in overall improvements.

Best for:

  • Significant amounts of weight loss

  • Those looking to build lean muscle mass

  • Those wanting to avoid all the risks associated with SARMs

#2 Safest SARM for Beginners: Ostarine MK-2866

Ostarine MK-2866

Ostarine MK 2866 is the SARM most people reach for on their first cycle. Known as one of the SARMs with the least amount of 'severe' sides that can actually stimulate fat loss and help with muscle growth.


Ostarine will bind to the Androgen Receptors in the body and increase muscle mass through biological changes via the mRNA. It can even improve your insulin sensitivity as well.

Ostarine MK 2866 also happens to be the SARM that has been researched more than any other but still has not been approved by the FDA for treatment yet.

Side effects are limited to nausea, cholesterol increase, and some liver strain.

Best for:

  • Those looking for a boost in lean body mass without suffering the sides

  • Can help reduce muscle wasting on a cut

#3 Safest SARM for Fat Loss: Stenabolic SR9009


Stenabolic SR9009

Stenabolic is not a SARM that gets a lot of attention purely because frankly, it certainly isn't the strongest SARM in the pot.

Stenabolic SR9009 is not actually a SARM after all but rather a REV-ERB which will increase the Rev-ErbA affinity in your body. It will help with your sleep pattern while also helping with fat loss as well.

It can decrease inflammation and it can also increase lipolysis. It won't do much for lean mass, but then again, you don't take it for that reason at all.

It won't need a PCT and won't lead to any Testosterone suppression.


Best for:

  • Those looking for a slight edge in fat loss

  • Can also improve your circadian rhythm

#4 Safest SARM for Bulking: Ligandrol LGD-4033

Ligandrol LGD-4033

Ligandrol LGD 4033 is actually one of the oldest and most well-known SARMs on the market. LGD 4033 was originally developed by Ligand Pharmaceuticals to aid patients suffering from muscle-wasting diseases but to have fewer side effects than Anabolic Steroids.

Skeletal muscle is the main part of the body that will react to LGD 4033. You might experience rapid muscle growth but more likely you will gain muscle at a normal rate. Athletic performance might improve, muscle recovery improves, and, unfortunately, your natural Testosterone production will drop.


Other side effects of LGD 4033 include aggression, acne, liver injury and kidney issues, and hypertension. Most of these are manageable with the right OTC medication, dietary supplements, and research chemicals.

Best for:

  • Those looking to improve the physical function of muscle cells

  • Can help with losing fat but will definitely increase anabolic activity

#5 Safest SARM for Strength: S4 Andarine

S4 Andarine

Andarine is another SARM that is considered by many who are only starting their journey. Known for being quite good at increasing muscle mass and strength but also has one or two side effects you need to be aware of.


It acts as a typical SARM by binding to the Androgen Receptors and causing a biological change through the mRNA. Just like Ligandrol it was developed to treat those suffering from muscle-wasting diseases but was developed by Gtx Inc.

Andarine also has the ability to reduce LDL (lipoprotein lipase) which is a bad kind of cholesterol. This can reduce the risk of liver damage and improve overall health, however, if you were to stack this with any of the other SARMs you might bring upon new adverse effects.

Andarine does not typically require a PCT because it does not reduce LH or FSH levels. Thus, no Testosterone suppression while building lean muscle mass.


Best for:

  • Those looking to gain muscle mass without severe side effects

  • Can help with overall health, but not a lot

Side Effects of SARMS

Side Effects of SARMS

The side effects of SARMs are hard to list seeing as there are so many different SARMs that work in different ways.

  • Androgenic side effects

  • Drop in Testosterone levels

  • Increased Estrogen (most usually manage this with a selective estrogen receptor modulator)

  • Hair loss

  • Insulin resistance (easily managed with diet and training)

  • Hepatotoxicity

  • Nephrotoxicity (a very dangerous one)

  • Yellowing of vision

  • Acne

  • Muscle cramps

Keep in mind that a lot of the side effects will depend on your dosage and duration of use, and also just common sense. For instance, since SARMs can/will boost IGF-1 it will be unwise for cancer patients to use them.


They will also require you to make use of a post-cycle treatment. If you fail to do this and you abuse SARMs you might end up needing testosterone replacement therapy for life. Unlike Anabolic Steroids it's unlikely this would happen but there is still a chance.

Benefits of SARMs

There are several different SARMs each with its own benefits you can consider:

  • Increase in lean muscle mass, growth, strength, and body weight

  • Greater bone density

  • Fat loss (weight loss)

  • Increased Basal Metabolic Rate due to more lean muscle tissue

  • Better muscle tone

  • (Some can) Improve skin, hair, and mood

One thing to note is that while SARMs can boost muscle growth and help you lose body fat it is unlikely they will ever be as strong as Anabolic Steroids. They have a vastly different chemical structure and they simply are not as strong despite what influencers might make you believe.


The one thing SARMs can do is specifically aid in fat loss, unlike Anabolic Steroids. None of the Anabolic Steroids (except Tren) has fat-burning properties, but SARMs like Cardarine and MK 677 (through Growth Hormone) can aid in fat loss.

In order to feel the full impact of SARMs you would need to engage in intense weight training while also doing everything you can to aid muscle recovery. Research chemicals are great but they won't work wonders.

Are SARMs better than Anabolic Steroids?

The selective androgen receptor modulator was developed to replace Anabolic Steroids since they literally have fewer side effects. They were developed to still help in building muscle while not wreaking havoc on the patient, like prostate cancer.


It wasn't long before individuals used (both of) them to improve athletic performance through muscle-building effects - hence why they are banned by the World Anti-Doping Agency.

Anabolic Androgenic Steroids have more side effects than SARMs, there is no denying that fact. However, SARMs do still have some SARMs. Although, they are certainly not as strong for muscle-building effects.

Clinical trials have been going well, however, human consumption has not been approved, hence why the only way you can purchase SARMs is via the 'not for human consumption' route; 'research chemicals, etc.

When the goal is building lean body mass you'll certainly benefit from using some of the SARMs listed here. They can all increase lean mass to some extent, and most can also lead to weight loss.


While safer than Anabolic Steroids, they do have quite a lot of anabolic activity. You can find plenty of SARMs for sale online that can help you build muscle. However, please practice safety and modesty when dosing your SARMs.

When trying to build muscle you should also be training hard, eating harder, and doing everything you can to improve skeletal muscle growth. Selective androgen receptor modulators can help, but they won't work miracles.


What are the safest SARMs for beginners?

Beginners should think very carefully before using SARMs. While they can improve muscle mass they do have side effects. The safest SARM is the Growth Hormone Secretagogue MK 677. Others include Ostarine MK 2866 and LGD 4033, the latter of which is a bit stronger and has more side effects. These are not dietary supplements, so, they are not regulated by any authorities, so, be careful.


Best SARMs for Muscle Growth

The 'best' SARMs for muscle growth are the ones that will have more adverse effects. We can't have everything at the same time. The stronger SARMs like YK11 will massively increase lean muscle mass but will have quite a few horrible sides.

Which SARMs are liver toxic?

Which SARMs are going to be liver toxic. Any drug that are used orally will have some hepatotoxicity about them. Most selective androgen receptor modulators will be liver toxic, but it's not the part you should be worried about (so much). The ones that affect your kidneys are the ones you should be careful about.

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