Alize Cornet won the match in straight sets (6-4, 6-2), thus ending Iga Swiatek's 37-match win streak.
Katie Boulter lost her grandmother a couple of days ago and her grandfather was present at the Centre Court to cheer for her. Boulter will next face Harmony Tan.
Serena Williams was given a wild card entry to Wimbledon this year. She will face France’s Harmony Tan in her first-round encounter.
It's at least the fourth known COVID-19 case among players who competed or planned to compete at the All England Club.
Serena Williams was returning to Wimbledon after being out of singles action for 364 days. Harmony Tan next faces Sara Sorribes Tormo.
Serena Williams has won seven Wimbledon championships, part of her total of 23 Grand Slam singles titles.
Harmony Tan is making her Wimbledon debut. The unseeded Frenchwoman next face either Coco Gauff or Amanda Anisimova.