In response to the 2026 MV Hondius hantavirus cluster, WHO issued a Disease Outbreak News alert and specific advice: States and operators should strengthen detection, infection control, ship sanitation, and coordination. Passengers and crew were advised to practice frequent hand hygiene, monitor symptoms for up to 45 days, ensure proper ventilation, avoid dry sweeping (to prevent aerosolising particles), and self-isolate if symptomatic. WHO assessed the global risk as low, with no evidence of wider community spread, but stressed ongoing surveillance and safe disembarkation protocols. WHO consistently promotes an “all-hazards” approach, recommending outbreak prevention and response plans (OPRP) on board, enhanced hygiene, ventilation improvements, food safety, water system maintenance, and collaboration between ship operators, port authorities, and national health agencies.