Amid the third Covid wave scare, lakhs of people all across the globe are getting vaccinating for coronavirus infection every day. The constant reports of new variants have made it extremely critical to keep a check on genetic mutations of coronavirus as they are a matter of concern. According to the American Food and Drug Administration, false-negative test results can appear due to the genetic variants of SARS-CoV-2 that are routinely generated, So far, the central government has denied such concerns of failure of RT-PCR testing.