Second seeds Daniil Medvedev and Aryna Sabalenka headlined Day 6 at Melbourne Park as top 10s Stefanos Tsitsipas, Felix Auger-Aliassime, Iga Swiatek joined them in the fourth round. Andrey Rublev, Roberto Bautista Agut and Anastasia Pavlyuchenkova were the big names to get knocked out.