Substitute Edin Džeko netted two goals, while Lautaro Martinez, Milan Skriniar, Nicolò Barella and Matias Vecino scored one apiece.
Emiliano Martinez saved three penalties in the shoot-out to help Argentina beat Colombia as Lionel Messi and Co set up Copa America 2021 final with Brazil
Lautaro Martinez was heavily linked with Barcelona but is happy he decided to remain alongside Romelu Lukaku at San Siro.
Inter saw off Sassuolo in Wednesday's rescheduled Serie A clash thanks to goals in either half from Romelu Lukaku and Lautaro Martinez.
Romelu Lukaku and Lautaro Martinez were on target for Inter at Torino as Antonio Conte's side sealed an eighth consecutive Serie A win
Lautaro Martinez scored twice and Romelu Lukaku was also on target as Inter overpowered rivals Milan 3-0, putting them four points at the top of Serie A
Romelu Lukaku and Lautaro Martinez both scored as title-chasing Inter claimed a comfortable 4-0 win over Benevento in Serie A
Inter accelerated away from poor Crotone in the second half of Sunday's San Siro clash to at least briefly take top spot in Serie A
Sassuolo's unbeaten start to the Serie A season came to an end as Inter expertly punished defensive errors in a 3-0 win
Lautaro Martinez was asked about his future on the eve of Inter's Champions League fixture at Shakhtar Donetsk.
Lionel Messi has been linked with a move from Barcelona, but the star looks "untransferable"
Inter 5-0 Shakhtar Donetsk: Lautaro Martinez and Romelu Lukaku each scored twice as Inter Milan made their first European final since 2010 in style
Goals from Danilo D'Ambrosio and Lautaro Martinez moved Inter back up to second ahead of their final Serie A match against Atalanta
Romelu Lukaku and Lautaro Martinez both scored as Inter claimed a 2-1 win over Sampdoria in Serie A
Inter star Lautaro Martinez has been linked with a move to Barcelona and Giuseppe Marotta discussed the forward's future again
Former Inter and Barcelona attacker Luis Suarez believes Lautaro Martinez should stay with the Serie A giants
Barcelona are not negotiating deals for Paris Saint-Germain star Neymar or Inter Milan forward Lautaro Martinez, according to La Liga president Javier Tebas