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SARMs Side Effects: What Are SARMs [Side Effects Of SARMs] And Legal Options For 2023

SARMs are not linked with same degree of dangerous side effects that are usually associated with anabolic steroids. This makes them considerably a safer choice for the fitness enthusiasts who want to increase their physical performance or build muscle mass. Click Here to See Legal Alternatives

SARMs Side Effects:

SARMs are a class of substances that have grabbed good popularity due to their similarities with traditional anabolic steroids. However, SARMs get an edge over anabolic steroids, as they are considered less harmful. 

SARMs are not linked with same degree of dangerous side effects that are usually associated with anabolic steroids. This makes them considerably a safer choice for the fitness enthusiasts who want to increase their physical performance or build muscle mass. Click Here to See Legal Alternatives

One of the main reasons why SARMs are considered less harmful than conventional steroids is because they target specific receptors in the body instead of affecting overall. 

The added testosterone situations throughout the body linked with anabolic steroids can invite a number of dangerous consequences and side effects, including reduced fertility, lack of libido, and hormonal imbalance. On the other hand, SARMs don’t bring on any sort of severe hormonal imbalance. 

Though, SARMs are known to be safer and friendly options for bodybuilders as compared to anabolic steroids, but still we cannot ignore the fact that SARMs are also not free from side effects. In this article, we will discuss the possible side effects of SARMs that you should be aware of before started using them. Also, we will discuss the respective side effects of some popular SARMs to give you a clear insight.

Side effects of SARMs

In spite of the fact that SARMs help greatly in bodybuilding and muscle development, we cannot deny the fact that are also accompanied with the side effects. 

Some of the common side effects of SARMs backed by the clinical studies are:

•    Testosterone suppression 
•    Acne or allergy 
•    Hair loss
•    Nausea
•    Gynecomastia
•    Loss of libido 
•    Liver toxicity
•    Headaches 
•    Mood swings 

This general side effects list will give you an idea that SARMs are also not safe to use. One has to keep in mind that these are some of the short-term negative effects, while the impact on long-term are still under research. Due to the many side effects of SARMs, WADA (World Anti-doping agency) has also listed SARMs in the banned category. This ban makes them prohibited to use by any athletes or sportsperson for the competition. 

SARMs Side effects Men

Many bodybuilders and fitness enthusiasts consider SARMs substances as a beneficial assistance to enhance their muscle building process. However, there are multiple side effects of consuming SARMs for both men and women. 

Most of the side effects are short-term, however, the impact of the side effects also depend on the consumption pattern of the SARMs by the individual. 

Some of the major SARMs side effects that are likely to occur in men are the following:

May Cause Liver Injury:Just like many anabolic steroids, SARMs may also cause liver injury. As per studies, the use of SARMs could cause cholestatic liver injury in human that could lead to medical conditions like jaundice or increased liver enzymes. Though, the occurrence of this side effects is rare except for the long-term usage of SARMs. This is the reason why liver injury cases occur more often in athletic circuits instead of recreational consumers. 


May increase hair loss: Most of the men face the issue of hair loss after reaching a certain age. However, hair loss largely depends on the genetics, environmental factors, and lifestyle as well. The usage of SARMs could also play a role in the male hair loss situations. 
There are different SARMs that cause the reduction in some hormone levels that may lead to hair loss in men. In addition, the over dosage of SARM for a long period of time could also bring the issue of hair loss. 

May cause Gynecomastia: SARMs may lead to cause gynecomastia in men and this is caused to the conversion of testosterone into estrogen and dihydrotestosterone (DHT) that occurs as a part of SARMs working mechanism. With the consumption of SARMs, maximum of androgen receptors gets occupied which left fewer androgen receptors for testosterone to bind. Due to this situation, more testosterone remain unbound, thus leads the elevated estrogen levels in males. This high estrogen level will lead to breast development in men, also known as gynecomastia. 

May Suppress Testosterone Production of the body: During the consumption of SARMs, your body gets so much filled with androgen that it kills the need of natural androgens in the body. The elevated androgens will indicate the body to reduce natural testosterone production in the body. In this the natural testosterone production in the body would be suppressed and at the same time, your body might begin exhibiting the signs and indications of low testosterone levels. 

May cause Acne Problems: SARMs could also be the reason of causing acne on your face. People with elevated T-levels may get the acne issues frequently. While using SARMs, the androgen level in the body gets increased, leading to terrible irregularities like acne on the face. The increased levels of androgen boost the sebum concentration on the skin, which prevents the skin from getting dried up. The oily skin condition will actually obstruct the removal of dead cells, thus cause the cell clogging and acne formation on the face.  


SARMs with least Side effects

If we can refer to the SARMs that offer the least side effects, then we would say that the safest SARM with least number of harmful impacts is LGD-4033 (Ligandrol). It is manufactured by Ligand Pharmaceuticals and is shown the safest among all SARMs variants. 

Many clinical studies have supports the fact that Ligandrol is comparatively safer to use than other SARMs, as it does not cause an increase in the levels of specific protein in the body that can lead to the risks of prostate cancer. 

Other than Ligandrol, the other comparatively safer SARMs with lease side effects are RAD 140 (Testol 140) and Ibutamoren MK 677 (Ibuta 677). 

SARMs RAD 140 Side effects

RAD 140 is one of the most popular SARMs, which is manufactured by a pharmaceutical company named Radius Health Inc. and is generally known as Testolone. RAD 140 is highly popular among the bodybuilding circuits, as it has all the positive traits of regular anabolic steroids. Initially, RAD 140 was created as a medical treatment for serious muscular wasting diseases, such as bone cancer, AIDS, cachexia, and muscle eating issues. 

Although, by no means RAD 140 can be compared to the serious side effects caused by the anabolic steroids, but still it has its own downsides. Some of the common RAD 140 side effects experienced by the users are listed below:

•    Nausea
•    Headache 
•    Aggression 
•    Hormonal Complaint 
•    Acne Issues
•    Hair loss

Fortunately, there are no serious toxicity related side effects associated with RAD 140 Testolone. By using PCT after the Testolone cycle, most of its side effects can be avoided and regularized. RAD 140 SARM is still under scientific research, as despite of some heavy benefits, it still impacts negatively on the consumer’s body. 


S4 SARM Side effects

S4 SARM, also known as Andarine, is a common and one of the most demanded among athletic circuits and bodybuilders who want to improve their weight-lifting abilities with an absolute endurance. S4 SARM is non-steroidal, means it has none of the side effects like anabolic steroids, but users have to worry for some other things while using S4 Andarrin. The side effects and their intensity will however most likely depend on the dosage of Andarine S4 SARM. 

Following are the side effects caused by S4 SARM:

•    Gynecomastia:S4 is responsible for stimulating prolactin hormone in the body which can cause male breast development, also known as gynecomastia. The sensitive users who may have earlier health issues such as liver and heart disease can more likely encounter this side effect. 
•    Cholesterol levels:Andarine S4 SARM also increases LDL cholesterol and improves HDL cholesterol which can trigger the risks of developing cardiovascular issues. 
•    Blood sugar levels:The over dosage of S4 Andarine for the long time leads to increase insulin resistance in the body that will spike blood sugar levels. 
•    Chances of liver failure:Taking S4 SARM in high dosage for long time duration can trigger chances of liver damage. This may be temporary or in some case permanent liver failure. 

S23 SARM Side effects

S23 SARM is considered as one of the most powerful SARM in the market. As per some clinical studies, it is known as more potent than S4 Andarine. S23 is a popular SARM to increase the muscle cells and strengthening bone tissues by mimicking the effects of testosterone. The use of S23 SARM makes the muscles rock-hard and encourage strength with better bone growth. This helps in preventing muscle lass in spite of helping in fat loss. Though, S23 SARM has many advantages, but still it is not perfect. 


As with other SARMs, it is also linked with some side effects that are mentioned below:

Testosterone production shutdown: While S23 mimics the testosterone hormone within the body, it decreases the body’s ability of naturally producing the testosterone hormone to such a degree that some users have to go for supplementation or testosterone replacement therapy to combat against this deficiency. 
Though, this suppression of T-levels is not a permanent side effects and can be reversed with the help of PCT after completing your S23 cycle. The PCT will help you in restoring the natural production speed of testosterone in the body. 

Anger Issues: The consumption of S23 may result in elevating the aggression. This side effect usually hit the people having history of anxiety issues. 

Testicle shrinkage: The use of S23 SARM may cause your testicles to shrink. This is because S23 SARM dominates testosterone without increasing the natural production of T-levels. However, this side effect is also temporary and normally get reversed after the completion of S23 cycle. 

Darker Colour of Urine: Though, this is not a worrisome side effects, but you must know that the dark urine will return to its normal color after you are finished with your S23 SARM cycle.

Chances of Hair loss: This side effect is not necessarily to be experienced by every S23 user. However, some may encounter hair loss during S23 cycle.

Most of the side effects only occur when S23 SARM is used in over dosage for extended periods of time. It is therefore important to use appropriate and recommended dosage to avoid the maximum side effects. 

LGD 4033SARM Side effects

LGD 4033, also known as Ligandrol was basically the drug for osteoporosis and muscular atrophy. However, it turned out to be one of the favourites of bodybuilding circuit because of its ability of muscle development and growth. Though, Ligandrol is considered as one of the most innocent member of SARMs class, and therefore doesn’t have any noticeable adverse side effects. However, we cannot take it as completely safe option, because of its strong effects. 

At broad levels, every drug and supplementation has its side effects, but due to the uniqueness of formula, some may not be tolerated by every user. Some of the negative side effects associated with the consumption of LGD 4033 SARM include: 

•    Suppression of natural hormones in the body; particularly testosterone suppression. 
•    Migraine attacks 
•    Mouth ache

Cardarine SARM Side effects

Cardrine SARM is one of the most impeccable cutting SARM that helps the user to achieve ripped and lean body.Cardarine SARM is used by the fitness lovers to enhance lean physique with added muscle mass while getting most out of their workouts.Cardarine is also known as GW 501516 in the market and is still illegal to use. This SARM is considered mild when taken in moderately low doses. 

In spite of its amazing benefits for fat loss , Cardarine is also associated with plenty of side effects that are listed below:

Headache:The most generally reported side effect of Cardarine SARM is severe headache. However, studies and user data have suggested that this side effect is substantially due to the over dosage during Cardarine administration. Severe headache could also be the result of using some medicines or substances simulatenously with Cardarine that beget headaches. 

Muscle Cramps:Another common side effect of Cardarine SARM is muscle cramps that is reported and experienced by numerous users. 

Diarrhoea:This side effect generally occurs among the users when they are consuming high dosages of Cardarine or when users are taking any such medicines alongside Cardarine that can cause diarrhoea symptoms. In some cases, some antibiotics and ibuprofen can cause diarrhoea while you are on Cardarine cycle. 
Pain in Joints:Some of the Cardarine users have also experienced pain in their joints. However, this is a temporary side effect and subsides within few weeks of starting treatment. 

Increased Heart Rate and Palpitations: The use of Cardarine SARM can also result in the sensation and feeling of elevated heart rate or palpitations. You may find this side effect really unpleasant, stressful, and painful. Though, generally it is not harmful, but could be a problem for people having history of any cardiovascular diseases. 

Elevated Blood Pressure levels: The administration of Cardarine may also lead to a severe spike in the blood pressure levels. This is a relatively serious side effect of Cardarine SARM, as it can put pressure on the heart. Also, heavy workouts and strength sessions during this issue can lead to severe cardiovascular events. This could be an adversely harmful effect for the people who suffers from pre-existing cardiovascular conditions. 

MK 677 SARM Side Effects

Ibutamoren, also known as MK 677 is a well-known SARM that plays an important role in gaining muscles within short span of time. It is highly appreciated by heavy weight athletes, bodybuilders and weight lifters due to its notable training advantages. Though, MK 677 is generally not associated with producing numerous side effects for its users that need to be concerned, but certain users have encountered some of the side effects by using this substance. 

People who have diabetes or insulin sensitivity are more prone to be on threat while taking MK 677. However, the symptoms associated with these medical conditions may get worsen with the use of MK 677. To avoid the maximum side effects, the correct dosing and operation of MK 677 is very important, as usually the side effects of MK 677 only came out in action when the doses are exceeding the recommended limit for the extended period of time. Some of the reported side effects by the MK 677 users are the following: 

•    Increased hunger cravings and appetite
•    Fatigue and anxiety
•    Pain in the body; especially if you have history of medical conditions or increased hormone situations. 
•    Insulin resistance
•    Possible increase in the prolactin levels; though it can be controlled. 

In spite of the above side effects, the adverse effects of MK 677 are simply minimum to none as compared from what you get from other stronger SARMs. 

Ostarine SARM Side effects

Ostarine is the popular SARM, also known as MK 2866. It is primarily used for trimming the body. It is called a combination of the two for being known as Enobosarm and GTx- 024. It helps in encouraging the muscle growth while strengthening the bones. It is appreciated and used by a large number of bodybuilders all around the world despite of being termed as illegal. 

Following are some of the serious negative effects that have been gathered as per the user reviews and studies: 

•    Stroke 
•    Heart attack
•    Liver damage

Due to these adverse effects, SARMs are not categorized as a fully safe substance to use. The above mentioned are the serious conditions that can even cause death. Particularly, MK 2866 might not cause severe acne issues, but still it offers some of the side effects related to testosterone suppression. 

Some of the other side effects associated with Ostarine MK 2866 are: 

•    Moderate acne
•    Violent headaches 
•    Common pain 
•    Muscle cramps
•    Constipation
•    Stress situations
•    Hair fall
•    High blood pressure

Though the adverse conditions and side effects are not caused by MK 2866 for every individual. But, to avoid the serious outcomes, the best way is to keep the doses within the recommended limits and also not to exceed the cycle length of Ostarine. 


Please understand that any advice or guidelines revealed here are not even remotely a substitute for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease.

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