One of the best combinations of two drugs for obesity is Phentermine-Topiramate which has been subjected to hundreds of clinical trials and proven to be effective against obesity.
Results were gathered after treating the patients for 1 year with 7.5 mg of phentermine and 46 mg of Topiramate. Participants who received Phentermine-Topiramate experienced over 6.7% weight loss and increased dosage takers remarkably lost over 8.9% body weight. Click here to see prices
Phentermine and Topiramate have been used differently since they belong to a different classes of drugs.
The expense provides by healthcare in the US only comprised $147 billion in 2008. Once you are in an obese circle, there are many expenses attached to your bills including medications, lifestyle modifications, and of course the diet.
Phentermine is a weight loss drug introduced to the medical community in 1959, the main purpose of this drug is to fight against excessive fat accumulation in the body by following multiple ways. Topiramate is a drug for epileptic seizures and Lennox-Gastaut syndrome and as a prophylactic treatment for migraine headaches, it was sooner recognized as a potential treatment for obesity in combination with Phentermine.
In 2012, FDA finally approved the use of Phentermine-Topiramate as a treatment for obesity in the United States.
Phentermine and Topiramate Reviews
Phentermine and Topiramate reviews are mixed that portray multiple feedbacks from the users.
If it’s about reducing blood sugar levels, the Phentermine-Topiramate combination is an excellent choice considering it's clinically proven to do so. However, using Phentermine-Topiramate for weight loss or anti-obesity reviews shows both negative and positive feedback.
Some users have experienced more side effects than the results.
Phentermine Topiramate Mechanism of Action
First of all, Phentermine by nature is a sympathomimetic amine that shares anorectic properties. The mechanism of action is the same as amphetamine which binds at the TAAR (trace amine-associated receptor) site and releases both epinephrine and norepinephrine in the central nervous system.
Topiramate on the other hand is an anti-convulsant drug that can stop seizures by acting on the higher sodium and calcium channel influx. Topiramate is a carbonic anhydrase inhibitor of the low type which has an antagonist effect on the glutamate receptors. Phentermine Topiramate in combination suppresses appetite and enhances the feeling of fullness in general and that’s why their Phentermine-Topiramate turns out to be the strongest appetite suppressant.
Phentermine-Topiramate Weight Loss
There are millions of cases reported since 2015 where obesity led to premature deaths around the world. Not just it, obesity reduces the quality of life and it has been mainly observed in US adults in which 35% of men and 35.8% of female are obese.
Based on clinical evidence, Phentermine-Topiramate in extended-release form was tested on up to three thousand obese patients. Another group was taken which on a placebo whereas lifestyle modification and a reduced calorie diet with daily physical workouts were also taken care of.
Phentermine-Topiramate Brand Name
It’s an extended-release form of Phentermine-Topiramate which is used for weight loss nowadays.
Physicians recommend Qsymia to morbidly obese patients who are on the brink of having cardiovascular problems due to obesity. Because Phentermine-Topiramate are controlled substances their daily intake requires a prescription because it might cause dependence in some users.
Qsymia is an expensive brand and should only be taken with proper medical guidance.
Phentermine-Topiramate Side Effects
One of the common side effects of Phentermine-Topiramate capsules is trouble sleeping and mood or behavioral changes. Qsymia brand of Phentermine-Topiramate is known to induce depression and anxiety in which case they should be informed to the doctor.
Phentermine-Topiramate users may also notice memory retention problems, speech impediments, and lack of concentration. That’s how you will be directed to the confusion and difficulty in attaining concentration.
Some users also noticed metabolic acidosis, a condition in which acid levels rise in the bloodstream. If left untreated, metabolic acidosis caused by Phentermine-Topiramate could also lead to kidney stones, osteoporosis, osteomalacia, and a slow rate of growth in children. Symptoms of metabolic acidosis involve loss of appetite, arrhythmia, lethargy, and trouble thinking.
Phentermine-Topiramate is also associated with high blood pressure which is also not to be taken with anti-hypertensive medications. Inform your physician about this if you are already taking B.P. medicines.
Phentermine-Topiramate side effects on Central Nervous System are:
Drinking alcohol with Phentermine-Topiramate might also exacerbate these side effects.
Where to Buy Phentermine Topiramate Online
Nowadays, it's really hard to find Phentermine-Topiramate in retail pharmacy US, UK, Canada, and Australia. You can easily purchase Qsymia (Phentermine-Topiramate) from the online option which is actually the official site of Qsymia. Click here to visit official website
You can find Phentermine-Topiramate at the lowest price from the official site with Home Delivery.
The phentermine-Topiramate price depends on several factors, the dosage, location for purchase, and quantity that you buy for your condition.
Phentermine-Topiramate Extended Release Oral Capsule costs for different doses are mentioned below.
- Phentermine-Topiramate 3.75 mg – 23 mg 30 capsules: $199.91
- Phentermine-Topiramate 7.5 mg – 46 mg 30 capsules: $205.36
- Phentermine-Topiramate 11.25 mg – 69 mg 30 capsules: $219.57
- Phentermine-Topiramate 15 mg – 92 mg 30 capsules: $219.57
That depends on your medical condition, body weight, and current state of your blood sugar levels. The phentermine-Topiramate dose also varies based on the time of the day you take these doses, the gap you provide between doses, and the duration of the entire cycle.
If it's for weight loss Phentermine-Topiramate dosage for adults and children 12 years of age and older, one capsule of Phentermine-Topiramate is taken every day for 2 weeks.
After 14 days, the doctor may also suggest increasing the dosage a little, at this point you will start taking 7.5mg phentermine with 46mg topiramate dose once daily, completing 12 weeks. The same cycle goes for 2 more weeks during which the doctor might also recommend gradually increasing the Phentermine-Topiramate dose.
Frequently Asked Questions about Phentermine-Topiramate
Q1: Does Phentermine work better with Topiramate?
Analyzing the potential of the Phentermine-Topiramate combination took around many years to culminate. A significant degree of weight loss is achieved in most patients who received Phentermine-Topiramate combination therapy for treating chronic obesity and the problems associated with it. Besides achieving the desired results, findings for Phentermine-Topiramate results also noted improvements in related blood pressure and sugar levels with a marked reduction in waist circumference.
The phentermine-Topiramate combination is also therapeutically beneficial against atherosclerosis and certain vascular conditions that portrays higher risk in the heart and pulmonary system. Obese patients experience sleep apnea occasionally and this problem can also be treated using Phentermine-Topiramate doses moderately.
Q2: How long does it take to lose weight on Phentermine Topiramate?
The minimum time period for Phentermine-Topiramate use is 3 months and after this period you could lose around 3% of body weight. Phentermine-Topiramate 6 months of use leads to a 5-7% reduction in body weight, some people lose more weight than others.
Let’s see what this means, for a person who weighs 200 pounds 5-7% weight loss means 10-15 pounds of body weight reduction. Not every user experiences the same results, some may not lose such kind of weight after 3 months.
Q3: How do phentermine and topiramate make you feel?
Phentermine Topiramate combination therapy is known to make users feel agitated and irritable. Some patients also stated they experienced suicidal thoughts and depressive episodes that made them feel vulnerable to the outside environment. If you notice any such types of side effects, you must inform your doctor pronto.
Q4: How long can you take phentermine and topiramate?
It is not recommended to take Phentermine-Topiramate for more than 12 weeks, especially if they haven’t lost 5% of body weight. It is also not recommended to take Phentermine Topiramate for weight loss for females who are pregnant and continuing the therapy might lead to teratogenic effects.
Weight loss drugs are many and none of them are available in combination with other compounds except Qsymia.
The rare but effective combination of Phentermine-Topiramate simultaneously treats patients with cardiovascular and metabolic complications due to an overweight issue. It’s not so long time ago since FDA approved the use of Phentermine-Topiramate for weight management.
Both of the medications have side effects and can be safer if used under a doctor’s supervision. If you received or notice any side effects such as anxiety, restlessness, insomnia, or changes in breathing patterns, Phentermine-Topiramate therapy should be discontinued.
The synergistic combination of Phentermine and Topiramate tends to produce adrenaline and dopamine in the brain that curbs the binge-eating and increases the metabolism of glucose which is the first thing diabetic people need. Men and women who are struggling to lose weight cannot necessarily lose weight by Phentermine-Topiramate, some people react negatively to this combination and must not use them.
You can find some unique forms of over-the-counter diet pills which have been known for work like Phentermine-Topiramate without side effects. Prescription-based medications for weight loss are always a bit risky choosing which you would be sacrificing the body systems.
Please understand that any advice or guidelines revealed here are not even remotely a substitute for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease.
The above is a sponsored post, the views expressed are those of the sponsor/author and do not represent the stand and views of Outlook Editorial.